Mycology Flashcards
what are fungi
eukaryotic organisms with chitin cell walls and ergosterol plasma membranes
what are yeasts, name some examples
single cellular fungi that bud to replicate e.g. candida, cryptococcus and histoplasma
what are moulds and name some examples
multicellular hyphae that grow by branching. e.g. dermatophytes, aspergillus, agents of mucormycoses
what is the most common cause of fungal infection in humans
candida
Treatment for oral thrush
nystatin
treatment for vulvovaginitis
fluconazole oral or cotrimazole topical
Investigations for disseminated candida
imaging, serology for beta D glucan, ECHO, fundoscopy
management of disseminated candida
2 weeks+ antifundals e.g. echinocandin
cryptococcosis serotypes a+D, vs serotypes B+C
A+d cryptococcus neoformans In immunocompromised, b+C cryptococcus gattii in immunocompetant
which animal is cryptococcus associated with
pigeons
risk factors for cryptococcus
impaired t cell immunity
cryptococcus gattii
causes meningitis in immunocompetent individuals in tropical latitudes, high incidence of SOL in brain and lung
what type of ink is used for cryptococcal stain
india ink
Cryptococcus management
induction (amphotericin), consolidation (fluconazole) and maintenance, repeat LP
Pneumocytis jirocerci
ubiquitus aspergillus