Lymphoma 031121

Question 1

how do you diagnose and stage lymphoma

Answer 1

histological diagnosis, anatomical stage (CT, PET BM biopsy, LP). Bloods (LDH, albumen, kidney, HIV +Hep B serology)

Question 2

how are non hodgkins lymphomas divided

Answer 2

B cell, T cell, premature, mature, grade

Question 3

hodgkins lymphoma epidemiology

Answer 3

Male more than female, bimodal age incidence,

Question 4

how is hodkins lymphoma staged

Answer 4

ann-arbor, (one lymph node region, 2 lymph node regions, two LN regions on opposite sides of diaphragm, extranodal sites)

Question 5

hodgkins lymphoma diagnosis

Answer 5

CT PET, LN or BM biopsy, reed sternberg cells (owl eyes)

Question 6

treatment of hodgkins

Answer 6

chemotherapy, ABVD (ADRIAMYCIN, BLEOMYCIN, VINBLASTINE, DACARBAZINE), radiotherapy but gives breast cancer risk

Question 7

burkitts lymphoma translocation n

Answer 7

t(8;14)

Question 8

three types of burkitts

Answer 8

endemic, sporadic, immunodeficiency

Question 9

histology or burkitts

Answer 9

starry sky

Question 10

diffuse large b cell lymphona epidemiology

Answer 10

middle aged and elderly, aggressive, richters transformation other lymphomas occur secondary to it

Question 11

follicular lymphoma epidemiology

Answer 11

indolent, mostly incurable, median survival 12-15

Question 12

follicular lymphoma histology

Answer 12

follicular pattern, nodular appearance

Question 13

mantal cell lymphoma histology

Answer 13

angular nuclei

Question 14

most common subtype of HL

Answer 14

Nodular sclerosing is most common

mixed cellularity, lymphocyte rich, lymphocyte depleted

Question 15

monitoring is appropriate for which lymphoma

Answer 15

follicular

Question 16

CLL staging

Answer 16

binet

Question 17

CLL clinical features

Answer 17

symmetrical painless lymphadenopathy, BM failure, FLAWS (B symptoms), hepatosplenomegaly, associated with autoimmunity, can progress to lymphoma