Diabetes Cases 150921 Flashcards
What is osmolality equation
Charged molecules + uncharged molecules + anions + urea + glucose
2(Na+K) +u+g
Cations
Na/K
Anions =
Cl, bicarbonate, others
Anion gap
Na+k-cl-bicarbonate
Normal anion gap is
18
What happens to calcium when ph falls
Proteins start to stick to calcium more than usual and decrease it
Hyperglycaemic hyperosmolar state
Severe dehydration in diabetes
Hyperosmolar non ketotic coma
HONK
Metformin effect on lactate
Lactic acidosis as inhibits the lactate conversion to glucose
Definition of type 2 diabetes diagnosis fasting and glucose tolerance test
Fasting plasma glucose of >7mM
Or
Glucose tolerance test plasma glucose or >11.1 at 2 hours
2h 7.8 -11=impaired glucose tolerance
Hba1c >48