Mycobacterium spp. Flashcards
Mycobacterium spp.
gram - or +
aerobe or anaerobe
acid fast? like what other bacteria
gram +
aerobe
acid fast like Rhodococcus, Nocardia
M. tuberculosis
gram - or +
aerobe or anaerobe
host:
reservoirs:
transmission:
pathogenesis:
clinical signs:
gram +
aerobe
human adapted pathogen, rare in non-primates
infected animals/humans
transplacental, milk, resp secertions
latency, reactivation, dissemination
granulomas, lung lesions
M. bovis
gram - or +
aerobe or anaerobe
host:
reservoirs:
transmission:
pathogenesis:
clinical signs:
gram +
aerobe
broad host range - animals/humans
infected animals/humans
transplacental, milk, resp secretions
latency, reactivation, dissemination
granulomas, lung lesions
describe the TB test…
hypersensitivity?
CFT?
CCT?
type IV hypersensitivity
Caudal Fold Test - M. bovis, if + then CCT necessary
Comparative Cervical Fold Test -M. bovis or M.avium
M. bovis & M. tuberculosis control/prevention
BCG vaccine (human only)
testing of herds
quarantine/depopulation
no raw milk
no abx in food animals
M. avium
gram - or +
aerobe or anaerobe
species:
clinical signs:
gram +
aerobe
cats
thoracic masses, mesenteric LN
M. avium complex
gram - or +
aerobe or anaerobe
species
pathogenesis:
clinical signs:
gram +
aerobe
rare in domestics, some zoo, sporadic in poultry/wild birds, IC people and small children
highly contagious
immunocompromised = weight loss, muscle atrophy
children = cervical lymphadenitis
M. avium paratuberculosis
gram - or +
aerobe or anaerobe
host:
reservoirs:
transmission:
pathogenesis:
clinical signs:
gram +
aerobe
dairy cattle > beef cattle
infected animals
shed in feces, colostrum, milk, in-utero
infected during early calf-hood, signs don’t show until 3-5yr of age
“Johne’s disease” granulomatous enteritis/wasting
when is Johne’s disease typically diagnosed
> 2 yrs of age
what are the rapidly growing mycobacteria (RGM) aka can grow in culture < 14 days?
M. abscessus
M. smegmatis
M. chelonae
M. fortuitum
M. abscessus
M. smegmatis
M. chelonae
M. fortuitum
clinical signs?
pathogenesis
pyogranulomatous inflammation, deep tissue infections w/ draining tracts
associated with tattoos & plastic surgery; non-contagious
differential diagnosis for RGM
Nocardia, Actinomyces, Fungi
diagnostics for RGM
aerobic, anaerobic, fungal and mycobacterial cultures (RGM grows in aerobic) - 3-14 days
what are the uncultivable mycobacterium spp.
“skin tuberculosis of cattle”
M. lepraemurium
M. leprae
Canine Leproid Granuloma
“Skin Tuberculosis” of cattle
species
clinical signs
cattle
lesions on lower limbs
M. lepraemurium
species
clinical signs
felines
Feline Leprosy (lesion on extremities)
M. leprae
species
clinical signs
pathogenesis
humans, non-human primates, armadillos
granulomatous disease
prefers skin due to low temp
Canine Leproid Granuloma
species
clinical signs
canine
nodular/ulcerated masses
