Mycobacterium spp. Flashcards
Mycobacterium spp.
gram - or +
aerobe or anaerobe
acid fast? like what other bacteria
gram +
aerobe
acid fast like Rhodococcus, Nocardia
M. tuberculosis
gram - or +
aerobe or anaerobe
host:
reservoirs:
transmission:
pathogenesis:
clinical signs:
gram +
aerobe
human adapted pathogen, rare in non-primates
infected animals/humans
transplacental, milk, resp secertions
latency, reactivation, dissemination
granulomas, lung lesions
M. bovis
gram - or +
aerobe or anaerobe
host:
reservoirs:
transmission:
pathogenesis:
clinical signs:
gram +
aerobe
broad host range - animals/humans
infected animals/humans
transplacental, milk, resp secretions
latency, reactivation, dissemination
granulomas, lung lesions
describe the TB test…
hypersensitivity?
CFT?
CCT?
type IV hypersensitivity
Caudal Fold Test - M. bovis, if + then CCT necessary
Comparative Cervical Fold Test -M. bovis or M.avium
M. bovis & M. tuberculosis control/prevention
BCG vaccine (human only)
testing of herds
quarantine/depopulation
no raw milk
no abx in food animals
M. avium
gram - or +
aerobe or anaerobe
species:
clinical signs:
gram +
aerobe
cats
thoracic masses, mesenteric LN
M. avium complex
gram - or +
aerobe or anaerobe
species
pathogenesis:
clinical signs:
gram +
aerobe
rare in domestics, some zoo, sporadic in poultry/wild birds, IC people and small children
highly contagious
immunocompromised = weight loss, muscle atrophy
children = cervical lymphadenitis
M. avium paratuberculosis
gram - or +
aerobe or anaerobe
host:
reservoirs:
transmission:
pathogenesis:
clinical signs:
gram +
aerobe
dairy cattle > beef cattle
infected animals
shed in feces, colostrum, milk, in-utero
infected during early calf-hood, signs don’t show until 3-5yr of age
“Johne’s disease” granulomatous enteritis/wasting
when is Johne’s disease typically diagnosed
> 2 yrs of age
what are the rapidly growing mycobacteria (RGM) aka can grow in culture < 14 days?
M. abscessus
M. smegmatis
M. chelonae
M. fortuitum
M. abscessus
M. smegmatis
M. chelonae
M. fortuitum
clinical signs?
pathogenesis
pyogranulomatous inflammation, deep tissue infections w/ draining tracts
associated with tattoos & plastic surgery; non-contagious
differential diagnosis for RGM
Nocardia, Actinomyces, Fungi
diagnostics for RGM
aerobic, anaerobic, fungal and mycobacterial cultures (RGM grows in aerobic) - 3-14 days
what are the uncultivable mycobacterium spp.
“skin tuberculosis of cattle”
M. lepraemurium
M. leprae
Canine Leproid Granuloma
“Skin Tuberculosis” of cattle
species
clinical signs
cattle
lesions on lower limbs
