Mutations Flashcards

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1
Q

Point

A
Single base pair changed
insertion / addition
Deletion
Substitution 
Most common
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2
Q

Bigger

A

Translocation
Deletion
More than single base pair
Inversion

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3
Q

Mutations

A

DNA had changed

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4
Q

Wild type

A

No mutated

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5
Q

Mutations three categories

A

Chemical energy
high energy radiation
Some viruses

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6
Q

Examples of high energy radiation

A

X rays

Ultra violent sunlight

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7
Q

Examples of viruses

A

HIV

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8
Q

HIV

A

Cause surgical cancer

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9
Q

Example of chemical

A

Gasoline, darkened meat, hot dog (nitrates turned to nitrosmein, hair dye

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10
Q

Carcinogen

A

Cause cancer

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11
Q

Carcenoman

A

Type of cancer

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12
Q

Inversion

A

Piece of DNA out own DNA and reinsert upside down or opposite directions

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13
Q

Deletion

A

Piece of DNA break off, is lost

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14
Q

Examples of deletion (bigger)

A

5 million base pair lost, autism

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15
Q

Effects of deletion and addition

A

Cause frame to shift = different amino acid sequence

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16
Q

Insertion / addition

A

Single base pair stuck, and doesn’t belong there

17
Q

Amino acid sequence

A

Determine secondary and tertiary structure

18
Q

Substituon

A

Have one base pair structure for another l

Cause amino acid to be different

19
Q

Examples of subsituoon

A

Sickle cell FFI

20
Q

FFI

A

Fatal familia insomnia

Will die when sleep

21
Q

Hemoglobin

A

In red blood cell
Transport oxygen
300 million in red blood cells
207 amino acids long

22
Q

Sickle cell

A

Cause red blood cells to be sickle shaped

23
Q

Translocation

A

Piece of DNA coming out of own DNA molecule and insert to different chromosome

24
Q

Why remove non coding

A

before leave nucleus have to remove non coding region of mRNA

25
Q

Coding

A

Codes for specific amino acid sequence

26
Q

Non coding

A

Not coding for amino acid sequence

27
Q

Splice some

A

Cut out introns

Reattach exons

28
Q

Result

A

Functional rna

29
Q

DNA printing

A

Use non coding DNA to determine junk DNA, use for determining ID

30
Q

What is splice some made out of

A

Protein, sRNA and other proteins

31
Q

Frame shift mutations

A

Insertions and deletions