mutations Flashcards
how many types of mutations are there
4
no mutation
the normal condition
missense
occurs when a change of a single base pair or group of base pairs results in the code for a different amino acid
nonsense
occurs when the change of a single base pair or group of base pairs results in a premature stop code in the gene.
silent
occurs when the change in one or more base pairs does not affect the functioning of the gene
frameshift
occurs when one or more nucleotides are inserted or deleted from a DNA sequence, causing the reading frame of codons to shift in one direction or the other.
spontaneous
Mutation is caused by an error during DNA replication
induced
Mutation is caused by the effect of an environmental agent
chemical
A particular chemical agent enter the nucleus and chemically alters the structure of DNA
electromagnetic radiation
- Lower energy radiation (e.g., UVB) can cause bonds to form between adjacent nucleotides creating a kink in the DNA backbone, which complicates replication and transcription
- Higher energy radiation (e.g., X-rays) can strip molecules of electrons and break bonds within the DNA molecule, which may result in a deletion or rearrangement of large portions of chromosomes