mutations Flashcards

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1
Q

how many types of mutations are there

A

4

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2
Q

no mutation

A

the normal condition

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3
Q

missense

A

occurs when a change of a single base pair or group of base pairs results in the code for a different amino acid

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4
Q

nonsense

A

occurs when the change of a single base pair or group of base pairs results in a premature stop code in the gene.

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5
Q

silent

A

occurs when the change in one or more base pairs does not affect the functioning of the gene

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6
Q

frameshift

A

occurs when one or more nucleotides are inserted or deleted from a DNA sequence, causing the reading frame of codons to shift in one direction or the other.

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7
Q

spontaneous

A

Mutation is caused by an error during DNA replication

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8
Q

induced

A

Mutation is caused by the effect of an environmental agent

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9
Q

chemical

A

A particular chemical agent enter the nucleus and chemically alters the structure of DNA

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10
Q

electromagnetic radiation

A
  • Lower energy radiation (e.g., UVB) can cause bonds to form between adjacent nucleotides creating a kink in the DNA backbone, which complicates replication and transcription
  • Higher energy radiation (e.g., X-rays) can strip molecules of electrons and break bonds within the DNA molecule, which may result in a deletion or rearrangement of large portions of chromosomes
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