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Core Drugs List (Yr2) > Musculosketetal > Flashcards

Musculosketetal Flashcards

1
Q

What are NSAIDs?

A

Non-steroidal inflammatory drugs

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2
Q

What do NSAIDs do?

A

Inhibit activity of cyclooxygenases (COX-1) and cyclooxygenases-2 (COX-2) and thus synthesis of prostaglandins and thromboxane. Leading to anti-inflammatory, analgesic (pain-killing) and antipyretic (fever-reducing) effects.

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3
Q

What do NSAIDs treat?

A

Symptomatic relief e.g. headaches, osteoarthritis ect.

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4
Q

What are three examples of NSAIDs?

A

Aspirin, ibuprofen, naproxen

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5
Q

What are DMARDs?

A

Disease-modifying anti-rheumatic drugs

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6
Q

What do DMARDs do?

A

Decreases pain and inflammation

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7
Q

What does DMARDs treat?

A

Reduce/ prevent joint damage in rheumatoid arthritis. Also for Crohns disease, lupus erythematosus

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8
Q

What are two examples of DMARDs?

A

Sulfasalazine, methotrexate

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9
Q

What does Colchicine do?

A

Prevents migration of neutrophils into the joint by binding to tubulin, resulting in the depolymerisation of the microtubules and reduced cell motility

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10
Q

What does Colchicine treat?

A

Gouty arthritis

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11
Q

What does Allopurinol do?

A

Reduces synthesis of uric acid by competitive inhibition of xanthine oxidase

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12
Q

What does Allopurinol treat?

A

Gout (recurrent attacks of inflammatory arthritis)

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13
Q

What does Betaxolol do?

A

Its a beta-blocker that reduces pressure within the eye (intraocular pressure)

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14
Q

What does Betaxolol treat?

A

Ophthalmic- glaucoma (build up of pressure in the eye that affects vision)

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15
Q

What does Prostaglandin analogues do?

A

Decrease eye pressure by decreasing fluid within the eye

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16
Q

What does Prostaglandin analogues treat?

A

Open- angle glaucoma

17
Q

What are two examples of Prostaglandin analogues?

A

latanoprost and bimatoprost

18
Q

What does Brimonidine do?

A

Decreases synthesis of aqueous humour by increasing the amount that drains from the eyes through uveoscleral outflow

19
Q

What does Brimonidine treat?

A

Open- angle glaucoma or ocular hypertension

Core Drugs List (Yr2) (9 decks)

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