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Core Drugs List (Yr2) > Infections > Flashcards

Infections Flashcards

1
Q

What are Penicillins?

A

Antibiotics

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2
Q

What do Penicillin treat?

A

Infections usually caused by gram-positive bacteria

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3
Q

How does Penicillin V treat infections?

A

By biosynthesis of cell0wall peptidoglycan

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4
Q

What does Penicillin V treat?

A

Mild-moderate infections e.g. respiratory tract

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5
Q

How does Amoxicillin treat infections?

A

By inhibiting the synthesis of bacterial cell walls. Inhibits cross-linkages between peptidoglycan polymer chains in Gram +ve and Gram -ve bacteria.

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6
Q

What does Amoxicillin treat?

A

Tonsillitis, bronchitis, pneumonia, ear, nose, throat and urinary tract infections.

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7
Q

How does flucloxacillin treat infections?

A

It binds to penicillin-binding proteins and inhibits peptidoglycan cross linking (its not inactivated by beta-lactamases)

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8
Q

What does flucloxacillin treat?

A

Ear infections, skin infections, bone and joint infections

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9
Q

How does co-amoxiclav treat infections?

A

Interferes with cell wall formation, inhibits action of beta-lactamases.

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10
Q

What does co-amoxiclav treat?

A

bacteria resistant to amoxicillin. It treats sinus, urine and joint infections. Also used before surgery to prevent infections.

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11
Q

What do cephalosporin do?

A

Disrupt the synthesis of the peptidoglycan layer

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12
Q

What do cephalosporin treat?

A

Ear, nose, throat, lungs, sinuses and skin infections

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13
Q

What are two examples of cephalosporin?

A

cefadroxil, cefotaxime

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14
Q

What does tetracycline do?

A

Inhibits protein synthesis-bacteriostatic

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15
Q

What does tetracycline treat?

A

Pneumonia, respiratory tract infections, acne, infections of skin, treats H.pylori, urinary tract infections.

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16
Q

What are three examples of tetracyclines?

A

Tetracycline, oxytetracycline, demeclocycline

17
Q

What do Macrolides do?

A

Inhibit bacterial protein synthesis

18
Q

What do Macrolides treat?

A

Respiratory, skin, soft tissue, H.pylori infections ect.

19
Q

What are two examples of Macrolides?

A

erythromycin, clarithromycin

20
Q

What does Trimethoprim do?

A

Binds to dihydrofolate reductase and inhibits reduction of dihydrofolic acid- this inhibits bacterial DNA synthesis

21
Q

What does Trimethoprim treat?

A

Urinary tract infections

22
Q

What is Metronidazole?

A

A antibiotic and a antiprotozal drug

23
Q

What does Metronidazole do?

A

Inhibits nucleic acid synthesis by disrupting the DNA of microbial cells

24
Q

What does Metronidazole treat?

A

Anaerobic infections, pseudomembranous colitis, stomach, skin, joint and respiratory tract infections.

25
Q

What does Ciprofloxacin do?

A

Inhibits DNA gyrase and enzymes necessary to separate bacterial DNA so inhibits cell division

26
Q

What does Ciprofloxacin treat?

A

A wide range of infections, including urinary tract infections and abdominal infections

Core Drugs List (Yr2) (9 decks)

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