Musculoskeletal - Amboss Flashcards
Name the disease(s) associated with antibodies against the following:
Myeloperoxidase
Microscopic polyangiitis
Eosinophilic granulomatosis with polyangiitis
(p-ANCA is an anti-myeloperoxidase antibody)
Name the disease(s) associated with antibodies against the following:
Centromeres
CREST syndrome
Name the disease(s) associated with antibodies against the following:
Voltage-gated calcium channels
Lambert-Eaton syndrome
Name the disease(s) associated with antibodies against the following:
La protein
Sjögren syndrome
Name the disease(s) associated with antibodies against the following:
Ro protein
Sjögren syndrome
Name the disease(s) associated with antibodies against the following:
SCL-70
Diffuse systemic sclerosis
Name the disease(s) associated with antibodies against the following:
Mi-2
Dermatomyositis
Polymyositis
Name the disease(s) associated with antibodies against the following:
Jo-1
Dermatomyositis
Polymyositis
Name the disease(s) associated with antibodies against the following:
SRP
Dermatomyositis
Polymyositis
Name the disease(s) associated with antibodies against the following:
Histones
Drug-induced lupus
Dislocation of the lunate is most likely to disrupt which nerve?
What is another serious complication?
The median n.
Avascular necrosis
Anesthesia of the dorsal aspect of digits 1, 2, and 3 is likely a result of what?
Radial nerve neuropathy
(often due to a tight watch or handcuffs, etc.)
Tenderness of the anatomic snuffbox is most commonly due to what?
Scaphoid fracture
Involuntary contraction of the interphalangeal joints in digits 1, 2, and 3 during attempted finger extension indicates compression of what?
Guyon’s canal
(ulner nerve injury)
What are some of the S/Sy of muscle damage that can be seen in hypothyroidism (due to impaired carbohydrate metabolism)?
Elevated creatine kinase
+
Delayed muscle reaction
What medication class can be used to treat acute flares of rheumatoid arthritis and bridge to DMARDs (e.g. methotrexate, azathiopine, sulfasalazine, etc.)?
Glucocorticoids
Which muscle is responsible for flexion of the PIP joints?
Which muscle is responsible for flexion of the DIP joints?
Flexor digitorum superficialis
Flexor digitorum profundus
What motions do both the flexor digitorum profundus and superficialis both perform?
Which is only accomplished by the profundus?
Which is only accomplished by the superficialis?
Flexion of the wrist and MCP joints
Flexion of the DIP joints
Flexion of the PIP joints
A patient shows S/Sy of ulnar damage following a fall onto his medial hand.
What is the likely bone affected?
The hook of hamate
(pisiform fractures are very rare)
What is the key feature of developmental dysplasia of the hip?
Abnormal development of the acetabulum
Name the age range in which each of the following is typically seen:
Avascular necrosis of the femoral head
Developmental dysplasia of the hip
Femoral neck fracture
4 - 10 years
< 6 years
> 70 years
How should you treat pain (e.g. from osteoarthritis) in a patient with peptic ulcer disease?
Acetaminophen
Celecoxib
What repeated movement leads to medial epicondylitis (golf elbow)?
What repeated movement leads to lateral epicondylitis (tennis elbow)?
Wrist flexion
Wrist extension
What nerve travels through the obturator foramen?
Where is it going?
The obturator nerve
The thigh adductors
A pannus is a proliferation of what?
Granulation tissue
Name a few major complications of bisphosphonate use.
Mandibular osteonecrosis;
hypocalcemia, renal impairment, esophagiitis
Which bursa lies directly over the kneecap?
Which is superior?
Which is on the medial knee?
Prepatellar
Suprapatellar
Anserine
Where are Spigelian hernias found?
The linea semilunaris
(lateral to the rectus abdominis)
Osteosarcomas typically arise from what tissue?
The periosteum
(from mesenchymal stem cells)
Describe the location of these components in the cycle in which homocysteine and methionine interact:
Methionine
Homocysteine
S-adenosylmethionine
Propionyl-CoA
S-adenosylhomocyteine
(Homocysteine is methionine without the methyl group.)
What are a few causes of homocystinuria?
Methionine synthase deficiency
Cystathionine synthase deficiency
Overuse of the quadriceps during adolescence can lead to what condition?
Osgood-Schlatter disease
(Inflammation and potential avascular necrosis at the tibial tuberosity.)
A patient presents after being hit in the face with a baseball.
She shows periorbital swelling, her globe is posteriorly displaced, her infraorbital rim is tender to palpation, and there is limited upward gaze.
What would you be likely to see on X-ray?
Tear-drop sign
(Fracture into the maxillary sinus)
Identify the respective nerve(s) innervating the following muscles:
Supraspinatus
Deltoid
Subscapularis
Teres minor
Teres major
Infraspinatus
Serratus anterior
Suprascapular n.
Axillary n.
Suprascapular n.
Axillary n.
Lower subscapular
Suprascapular n.
Long thoracic n.
Where are the pain points of fibromyalgia found?
The entheses of certain sites like the back, neck, shoulders, and medial aspect of the knees
Identify the labeled portions of this image:
A)
B)
C)
D)
E)
Identify the labeled portions of this image:
A) I band
B) A band
C) H zone
D) M line
E) Z line
