Muscular Dystrophy

Question 1

What is reduced in muscular dystrophy?

Answer 1

Dystrophin production

Question 2

What is the most common form of MD?

Answer 2

Duchenne muscular dystrophy

Question 3

What is the inheritance of DMD and BMD?

Answer 3

X linked recessive

Question 4

What is gowers sign?

Answer 4

MD sign of children showing difficulty to raise from standing

Question 5

What is calf pseudohypertrophy?

Answer 5

Calfs look like inverted champagne bottles as muscle loss is replaced with fat

Question 6

Why is tip toe walking shown in MD?

Answer 6

Shortened achilles tendon - serial ankle bracing is used

Question 7

Which limbs are affected first in MD?

Answer 7

Starts proximally and moves distally
Lower limbs first

Question 8

What is the diagnosis for MD?

Answer 8

Creatinine kinase raised
Muscle biopsy

Question 9

What is the treatment for MD?

Answer 9

Corticosteroids
VD and calcium
Wheelchair
Creatinine supplements
Respiratory surveillance

Question 10

What is the most common cause of death in MD?

Answer 10

Weak diaphragm and respiratory failure

Question 11

What is the most common heart defect associated with DMD?

Answer 11

Dilated cardiomyopathy