muscles disease

Question 1

• genetic & breeding
• skeletal muscles double the normal size
• possible joint problems

Answer 1

Found in dogs
Bully Whippet

Question 2

-breeding
- bigger muscles
-more developed
-no treatment is needed

Answer 2

Belgian blue COW

Question 3

a genetic disease that causes muscles to weaken and degenerate over time.

-Genetic mutation; muscles become weak
-difficult walking
- Trouble with fine motor skills
- frequent falls
-physical therapy
-muscle regeneration
-mobility devices

Answer 3

Muscular dystrophy

Question 4

a rare autoimmune disease that causes chronic inflammation of the muscles, resulting in weakness and pain
- rashes around eyes & Knuckles
- joint and muscle swelling
-steroid treatment to combat autoimmune disease
- exercise to build up muscles

Answer 4

Myositis

Question 5

-Antibodies hinder neurotransmitters
-error in nerve to muscle communication
-droopy eyes
double vision
-difficulty with facial expressions
weak arms and legs and neck
-Medication
-IV treatment
-Surgery

Answer 5

Myasthenia Gravis; immune disease, voluntary muscles weak/tired.

Question 6

Neuromuscular disease; repeating muscle contractions muscle stiffness and increased muscle volume.
- Genetic mutation in CAV3 gene/can develop into autoimmune form
-sensitivity to movement or pressure
-repetitive muscle contractions/tensing
-muscle bunching/mounding
- Symptom management
-medications
-Thymectomy (removal of tumor in thymus gland)

Answer 6

Rippling Muscle disease

Question 7

progressive neurological disorder where the nerve cells in the brain and spinal cord that control voluntary muscle movement gradually deteriorate, leading to muscle weakness, paralysis, and eventually, death due to respiratory failure

-slurred speech
-muscle twitching and cramps
-clumsiness
breathing problems

Answer 7

ALS: Amyotrophic Lateral Sclerosis

Question 8

a rare genetic disorder that causes permanent muscle stiffness and abnormalities in the bones and skeletal muscles
- Mutation in the HSPG2 gene: does not allow the creating of certain proteins
- Abnormalities of skeletal muscles
- joint and muscle deformities
- muscle stiffness and contraction
-Botox for facial muscles
-surgery is needed.

Answer 8

Schwartz-Jamel Syndrome

Question 9

Delayed muscle reaction
- Mutation- electrical excitation
- Abnormal muscle appearance
- Pain
- Sodium channel blockers
-movement
-Tricyclic antidepressants

Answer 9

Myotonia

Question 10

A rare, congenital disorder that causes the absence of all four limbs
- Variants in genetic mutations
-Severe malformations of other body parts
difficulty breathing
-no treatment
-symptom management
-Assistive devices
- Therapy

Answer 10

TetraAmelia Syndrome

Question 11

Problem with CNS;
CAUSED BY:
- muscle/genetic disorder
-cerebral palsy
-down syndrome
-Marfan syndrome
low muscle tone or muscle weakness.
-floppy/ragdoll quality when held
-limbs extending beyond normal limit
-lack of motor skills
-problems feeding/breathing
Therapy : Speech, physical, occupational
- bracing/supportive equipment

Answer 11

Hypotonia

Question 11

A genetic disease that causes progressive muscle weakness and atrophy. It’s caused by the loss of motor neurons, nerve cells in the spinal cord and brain stem that control muscle movement.

-mutations in the SMN 1 gene; can be inherited
- muscle weakness
-breathing issues
-hypertonia
-scoliosis
-bed sores

-Zolgensma: gene replacement therapy
-Nusinersen injection
- physical therapy

Answer 11

Spinal muscular Atrophy
(SMA)

Question 11

group of neuromuscular diseases that cause muscle problems due to damage to mitochondria

-3 types of genetic mutations that impair the production of ATP.
-muscle weakness
-exercise intolerance
-restricted eye movement
-double vision
-droopy eyelids
-speech/swallowing problems
-no cure only support

Answer 11

Mitochondrial Myopathy