Muscles And Synapses Flashcards
3 types of neurons
Afferent
Ifferent
Interneurons
Afferent neurons
Carry info from periphery to spinal cord via dorsal roots, excititory
Ifferent neuron
Carry info form spinal cord to periphery via ventral roots, excitatory
Interneurons
Carry info between neurons, both excitatory and inhibitory
Glia cells produce?
Myelin
- Schwann cells in PNS
- olidogendrocytes in the CNS
Glia cells form the
Blood brain barrier
Glia ce3lls guide migrating
Neurons and direct animal outgrowth during development (radical glia)
Satellite glia
Produce strucure and support isolating neurons form 1 to another
Dentrites
Receive stimuli,
Dendrites produce generator or receptor potentials :
In motor neurons and association neurons, produce excitatory postsynaptic potentials (EPSP) and inhibitory postsynaptic potentials (IPSP)
Cell body
Receive stimuli and produce EPSPs and IPSPs through activation of chemically or mechanically gated ion channels
Junction of axon hillock and initial segment of axon
Trigger cone, integrates EPSPs and IPSPs and, if sum is a depolarization that reaches threshold, intimates potential (nerve impulse)
Axon
Propagates nerve impulse form initial segment (form dentrites) to axon terminals, impulse amplitude does not change as it propagates along the axon,
Axon terminals and synaptic end bulbs
Inflow of Ca2+ causes depolarization of nerve impulses trigger NT release by exocytosis of synaptic vesicles
Resting membrane potential
Measure of electrical potential difference between intercellar environment and extra cellular environment
(70mV)
What’s involved in primarily setting the resting membrane potential
Ions (K+ and Na+)
net - charge is set up by
Na/K pump
Na/K pump
- Electrogenic as it moves charge across memb.
- ATP hydrolysis
K wants to diffuse _______ the cell
Na wants to diffuse _______ the cell
K wants to diffuse out of the cell
Na wants to diffuse into the cell
Resting membrane potential is set by
Leak channels
Leak channels are
Alway open, allow passive flow of i9ons in and out of the neuron
Are leak channels selective ? What are they powered by ?
Yes. Powered by chemical and electrical gradients
Equilibrium potential is when the membrane potential at which the
Chemical conc. Gradient is balanced
K leak channel equilibrium pot.
-90mV
Na leak channel equilibrium pot.
+60mV
The m,ore permeant the ion, the
Greater the force Em towards its own equilibrium potential
Between K and Na, which has greater permeability
K, that’s why the RMP is closer to K then Na, at -70mV