CNS 3 Flashcards

1
Q

Neural signals of a given modality from a particular region of the body travel along specific pathways to the brain (Called

A

“labelled” or “private” lines).

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2
Q

The ability to locate a stimulus depends on the

A

size and density of receptive fields of the receptors.

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3
Q

Within the CNS, lateral inhibition focuses

A

ascending sensory signals, enhancing spatial acuity.

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4
Q

Ascending sensory axons synapse on neurons in the brainstem that then cross the

A

midline, conveying sensory information from the right side of the body to the left side of the brain and vice versa.

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5
Q

Two-point Discrimination

A

• Sensory afferent A has a smaller receptive field than afferent B, which provides greater spatial acuity

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6
Q

Overlapping Receptive Fields

A

Overlapping stimulation between neighboring receptive fields provides general information about the location of a stimulus

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7
Q

Divergence:

A

Each sensory afferent sends branches to many neurons in the CNS

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8
Q

Convergence

A

a given neuron in the CNS receives inputs from many sensory afferents

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9
Q

Lateral inhibition:

A

– “Sharpens contrast” by focusing activation of CNS neurons

– Stimulus location is perceived more precisely (↑ “acuity”)

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10
Q

Two-point discrimination is best on

A

hands and face, worst on abdomen and proximal parts of limbs

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11
Q

Two-point discrimination is best on hands and face, worst on abdomen and proximal parts of limbs

WHY?

A
  1. Density of receptors is highest in skin areas with the best 2-point discrimination
  2. Surface area of sensory cortex is largest in regions to which receptors from skin areas with the best 2-point discrimination project
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12
Q

The conscious awareness of a stimulus is called a

A

sensation

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13
Q

A sensation combined with an understanding of its meaning is called

A

perception

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14
Q

Are both sensation and perception a result form processing in the cerebral cortex?

A

YES

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15
Q

Topographic Maps are within the

A

Sensory cortex

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16
Q

Topographic maps Project area that’s related to

A

functional importance ie. Lips, tongue,
thumb, fingers in humans and monkeys; snout, periodontal tissue in
rabbits & cats

17
Q

Topographic Maps change according to use:

A

“plasticity” ie. Shoulder & arm areas
enlarge after below-elbow amputation.

  • constantly change, sometimes within seconds: “dynamic plasticity”.
18
Q

Descending Inhibition

A

Activity descending from higher centers in the brain and brainstem can “screen out” certain types of sensory
information by inhibiting neurons in the afferent pathway

19
Q

Presynaptic inhibition:

A

Acts by reducing transmitter release at synapse between first-order and second-order sensory neurons

  • inhibits specific sensation (pain)
  • lasts several seconds
20
Q

Postsynaptic inhibition:

A
  • acts by hyperpolarizing memb. Of second order sensory neurons
  • non-selective: reduces effect of all synaptic inputs
  • lasts less then 1 millisecond
21
Q

Analgesia

A

(Suppression of Pain)

  • aspirin
  • opioids
22
Q

Activity in the analgesic system in brainstem can suppress pain by releasing

A

“endogenous” opiate neurotransmitters onto pain fibre endings in spinal cord eg. During fright/fight reactions

23
Q

Projection neurons can also be inhibited by the firing of

A

large sensory afferents (eg. Those signalling touch, pressure, muscle stretch)

– Explains analgesia elicited during rapid movement and by acupuncture, rubbing the skin and transcutaneous electrical stimulation (TENS)

24
Q

Re ferred Pain

A

• Convergence of visceral and somatic
afferents on ascending projection neurons in the spinal cord

• Regions of body surface where referred pain from visceral organs is perceived

25
Q

Pain & temperature afferents synapse on 2nd-order interneurons in spinal cord that cross within 2 segments and ascend in the

A

spinothalamic (Anterolateral) tracts

26
Q

To uch, pressure and stretch afferents from muscle & skin ascend in the dorsal columns. They contact 2 nd-order neurons in brainstem and then cross to

A

contralateral side