Muscles And Syanpses L4 Flashcards
AP transmission
1) Axon at resting memb. Pot.
2) activation results in opening of voltage Na+ channels, local depol. Of the memb.
3) local depol. Of memb. Causes adjacent voltage gated Na+ channels to open
4) new AP generated in adjacent memb.
AP only travels in
1 directions due to refractory period (electronic condition)
Electronic conduction
Spread of current inside axon
how AP travels down axon
Electronic current flow is fast, but must be regenerated at every point on the memb., this would take to long, so how is this sped up?
Myelination
Myelination
- increases speed of EC
- Schwann cells in PNS
- obligendrocyes in CNS
Myelination is continuous or discontinuous
Discontinuous = nodes of ranvier
Many Schwann cells unsheathe
1 axon in the PNS
One oligodendrocyte ensheaths
many axons in the CNS
Saltatory conduction
AP being regenerated at the nodes of ranvier, but current flows electronically through nodes
Myelination increase speed of conduction by increasing efficiency of electronic conduction such that
AP doesn’t need to regenerate at every point of the axon
Classification of afferent fibre types
4 types,
Type 1 being thicker myelination = fastest
(Skeletal muscle propiocepter)
Type 2 = skin receptor
Type 3= pain and temp
Type 4 being thinner myelination = slowest
(Pain/itch/temp)