Muscle Tissue Flashcards
3 Type of Muscles
Skeletal, Cardiac, Smooth
Myo
Muscle
Sarco
Flesh
Epimysium
Exterior, Connected to Deep Fascia
Perimysium
Surrounds Muscle Bundles (fascicles) Contains BV and Nerves
Endomysium
Surrounds Individual Muscle Cell Capillarities, Nerve Fibers, Stem Cells
Structure of Muscles
Muscle Tissue, Connective Tissue, Nerves, BV
Muscle Fibers
Fusion of Myoblasts, Hundered of Nuclei
Sacroplasm
Cytoplasm of a MF
Sacrolemma
Cell Membrane of a MF
T-Tubles
Transverse Tubules, A Extension of Sarcolemma, Transmits Action Potential
Sacroplasmic Reticulum (SR)
Smooth ER of Muscle, Membrane Structure Surrounding the Myofibril (Storage of ca2+)
Triad
Terminal Cisternae (Enlarged SR) + TTubule= Diffusion (communicate)
Myofibril
Made of Myofilaments
Thin Filaments
Protein Actin
Thick Filaments
Protein Myosin
F-Actin
Whole Molecule, 2 Strands of G-Actin
G-Actin
Globular Protien
Structure of Myosin
Tail: Binds The Myosin Together
Head: Reaches For Actin
Sarcomere
Functional Unit of a Contraction, Z-Line to Z-Line
Z-Line
End of a Sacromere, made of actin and thin filaments.
M-Line
Middle of Sacromere, Stabilizes Myosin
A Band
Dark, Entire Myosin Range (Never Moves)
H Band
Only Myosin, (center) Thick Band, Thick Filaments
I Band
Only Actin, Thin Filaments
Zone of Overlap
H,I Bands
Titin
Tip of Myosin Filament to the Z-Line, Stabilizes Thick
Nebulin
Holds the F-Actin Together
Tropomyosin
Prevents Actin-Myosin Interaction (rest)
Troponin
Binds Tropomyosin to G-Actin, Controlled by ca2+
1st Step of Contraction
Actin Slides Toward M Line
2nd Step of Contraction
Zone Overlap Enlarges
3rd Step of Contraction
H Band shrinks and I Band Shrinks
4th Step of Contraction
A Band Unchanged
5th Step of Contraction
M Band Unchanged
6th Step of Contraction
Z Lines Move Closer Together
When Do Contractions Start?
When the Sarcolemma is Stimulated
The Neuromuscular Junction
1.) Synapse
2/3.) Neurotransmitter Acetylcholine
4/5.) Acetylcholine broken down by enzymes
Excitation/ Contraction Coupling
Electrical Signal to a Contraction
What Happens When a Muscle Contracts
Fiber Shorting, Relaxation
Fiber Shortening
Sacromere Shortens, Muscles pull together creating tension
Relaxation
Ca2+ is pumped out of the cell, Detaches
Rigor Mortis
Muscular Contractions After Death
Tension
All or Nothing, A Muscle Fiber is either contracted or released.
Cross Bridges
A Overlap in Actin/Myosin
Latent Period
STIMULI APLLIED, The Delay, Ca2+ release
Contraction Phase
Ca ions bind, Tension Builds
Relaxation Phase
Ca2+ levels decrease, active sites covered
Tetanus
Max Level of Tension
Summation
Max Force from each Fiber (tetanus)
Recruitment
Activates Motor Unit
Short Term Stimulation
15 Seconds
Anaerobic Glycosis
130 Seconds, No Oxygen, Breaks down glucose from glycogen to produce 2 ATP
Aerobic Metabolism
2400 Seconds, Oxygen, Uses Fatty Acids, Produces 34 ATP
The Cori Cycle
Removal and Recycle Lactic to Liver
Hormones
Growth, Testosterone, Thyroid, Epihphrine
Large Diameter
Stronger Contraction
Fast Fibers (Anaerobic ATP)
pro: Large Diameter, Strong Contraction
con: Fatigues fast
Slow Fibers (Aerobic Fiber ATP)
pro: Fatigues Slowly
con: Small Diameter
Intermediate Fibers
Fast Fibers, Good Blood Supply, Little Myogoblin
Hypertrophy
Increase In Cell Size
Atrophy
Decrease In Cell Size
Cardiocyte
Small, Single Nucleus, Short/Wide T, No Triads, Aerobic, Intercalated Discs. Hold Cells Together
Automaticity
Contraction Without Neural Stimulation
Variable Contraction
Nervous System
Extended Contraction
10x Skeletal (No Fatigue)
Prevention of Summation
Long Refractory Time
Smooth Muscle
Forms around other Tissues
Location of Smooth Muscle
BV, Reproduction, Glandular, Digestive, Urinary, Integumentary System
Forms created by Smooth Muscle
Spincters, Contractors, Arector Pilli, BP, and Aidgamates
Structure of Smooth Muscle
No T Tubules, Ca2+ not from SR, Long slender, spindled 1 nucleus NO BANDS
Multiunit Smooth M Cells
No Gap Junctions, Separate Fibers, Contract Independently.
Viseral Smooth M Cells
Many Gap Junctions, Syncytial Contraction (all cells), Spindle shaped.