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Muscle Relaxants Flashcards

1
Q 
Direct Acting Muscle Relaxant?
Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Dantrolene

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2
Q 
Centrally Acting (CNS) Muscle Relaxants
Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Diazepam
Baclofen
Cyclobenzaprine

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3
Q 
Multiple Sclerosis Agent:
Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Interferon beta 1a or beta 1b

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4
Q

Treat:
Malignant Hyperthermia
Relieve spasms related to cerebral palsy, spinal cord injuries, multiple sclerosis

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Direct Acting Muscle Relaxant:Dantrolene

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5
Q

MECHANISM OF ACTION
Acts directly on muscle spasms and inhibits muscle contraction via prevention calcium release in skeletal muscle

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Direct Acting Muscle Relaxant:Dantrolene

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6
Q

ADVERSE EFFECTS
Hepatotoxicity
Dizziness/Diarrhea

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Direct Acting Muscle Relaxant:Dantrolene

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7
Q 
ADVERSE EFFECTS
Drowsiness?
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Alll

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8
Q

Monitor
for adverse effects of malignant hyperthermia
Liver enzymes

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Direct Acting Muscle Relaxant:Dantrolene

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9
Q

Mnemonic - D’s = Dizziness/Diarrhea

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Direct Acting Muscle Relaxant:Dantrolene

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10
Q

Direct Acting Muscle Relaxant:Dantrolene

D-

A

Dizziness/Diarrhea

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11
Q

Administration
Powder form: For MH- you have to draw up lots of syringes of 50 ml of sterile water to start reconstituting these vials

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Direct Acting Muscle Relaxant:Dantrolene

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12
Q

Direct Acting Muscle Relaxant:Dantrolene
? form: For MH- you have to draw up lots of syringes of ? ml of sterile water to start reconstituting these vials

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Powder

50

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13
Q

Treat:
Relief of painful musculoskeletal conditions

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

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14
Q

Muscle spasms ◦Management of spasticity of severe chronic disorders (multiple sclerosis, cerebral palsy)-

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

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15
Q

typically used CHRONICALLY
Work best when used along with physical therapy

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

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16
Q

MECHANISM OF ACTION
Act to relieve pain associated with skeletal muscle spasms

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

17
Q

Dizziness/Sedation/Drowsiness/ Fatigue
Muscle weakness
Constipation/urinary retention

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

18
Q

Constipation/urinary retention

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

19
Q

Administration
Often given with food to reduce GI upset, If using chronically- DO NOT STOP SUDDENLY

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

20
Q

Wouldn’t drive the first time you take them

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Centrally Acting (CNS) Muscle Relaxants
Baclofen
Cyclobenzaprine

21
Q

Treat:
Multiple Sclerosis

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

22
Q

MECHANISM OF ACTION
immunomodulatory agent

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

23
Q

ADVERSE EFFECTS
“Flu Like” Reaction during administration
Bone Marrow Suppression
◦Interferon is an immunomodulatory!

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

24
Q

“Flu Like” Reaction during administration

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

25
Q

BOXED WARNING
Always premedicate with Acetaminophen

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

26
Q

BOXED WARNING
Interferons will cause “flu-like” symptoms◦“

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

27
Q

Nursing Considerations
Not recommended to give with other immunomodulatory agents (like steroids)

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

28
Q

Mnemonic
Interferons interfere with you”
Narrow Therapeutic Index

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

29
Q

Monitor
CBC, immunological function

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

30
Q

Administration
Interferons (regardless for MS or certain leukemia, etc.) are Parenteral agents◦Subcutaneous, IV, IM

Diazepam
Interferon beta 1a or beta 1b
Baclofen
Dantrolene
Cyclobenzaprine
A

Multiple Sclerosis Agent:Interferon Beta-1a and Beta-1b

Phamacology (13 decks)

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