Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Phamacology > Acid Controlling Drugs > Flashcards

Acid Controlling Drugs Flashcards

1
Q 
Antacids?
Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Antacids: aluminum, magnesium salts, calcium salts, sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
H2RA's (Histamine2 Receptor Antagonists)?
Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Histamine 2 Receptor Antagonists (H2RA) : cimetidine 1st Generation, & Ranitidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q 
Proton Pump Inhibitors?
Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Proton Pump Inhibitors/PPI: Omeprazole, “Prazole”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q 
Anti-Ulcer Agents?
Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q 
Extra?
Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Extra
Simethicone
Bismuth Subsalicylate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Treat:
GERD/Heart burn
ALUMINUM- (Hyperphosphatemia) due to CKD (except magnesium!)
NOT for treating PUD
Many antacid combinations include simethicone to reduce the surface tension of gas bubbles

Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Antacids: aluminum, magnesium salts, calcium salts, sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ALUMINUM- (Hyperphosphatemia or Hyperphosphatemia) due to CKD (except pottasium or magnesium!)

A

Hyperphosphatemia

Magnesium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q 
NOT for treating PUD?
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

(aluminum, magnesium salts, calcium salts, sodium bicarbonate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q 
Many antacid combinations include ? to reduce the surface tension of gas bubbles?
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

simethicone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Neutralize gastric acid (hydrochloric acid) by producing neutral salts

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

aluminum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Antacids: Aluminum Salts

Has constipating effects. Often used with (Pottasium or magnesium) to counteract constipation.

A

magnesium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Can be used in CKD to treat hyperphosphatemia?

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

aluminum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
Antacids: Magnesium Salts
Commonly cause (Constipation or Diarrhea) with other drugs.
A

Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

CONTRA-INDICATION
Dangerous when used with renal failure; the failing kidney cannot excrete extra (pottasium or magnesium) resulting in (Retention or Accumulation)

A

magnesium

Accumulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cause
Constipation, Kidney stones, Milk Alkali Syndrome (don’t give with milk!), Rebound Hypersecretion of Acid

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

calcium salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Long duration of acid action—may cause increased gastric acid secretion (hyperacidity rebound)

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

calcium salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Often advertised as an extra source of dietary calcium (such as Tums®)

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

calcium salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

don’t give with milk!

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

calcium salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Antacids: Sodium Bicarbonate

Lowly or Highly soluble

A

Highly soluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Buffers the acidic properties of HCl

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Quick onset but short duration

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

May cause metabolic (alkalosis or acidosis)

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

alkalosis

sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

? content may cause problems in patients with heart failure (HF), hypertension, or renal insufficiency.

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Constipation:

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

Aluminum/Calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Diarrhea:

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

Magnesium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

? is given for CKD (hyperphosphatemia)

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

Aluminum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Heart Failure: Avoid any that have ?

aluminum
magnesium salts
calcium salts
sodium bicarbonate

A

SODIUM (Sodium Bicarb)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Antacids: aluminum, magnesium salts, calcium salts, sodium bicarbonate

Generally ? to ? hours after a meal, bedtime too
Reminder to take other medications before or after if possible to avoid any binding problems or absorption issues (minimum ?-? hour window- both directions)

A

1 to 3 hours

1-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

If someone is using chronically, we need to investigate!

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Antacids: aluminum, magnesium salts, calcium salts, sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

MECHANISM OF ACTION
Antagonizes H2 receptors in gut; Decreases acid production; Increases pH in stomach, decreases damage

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Histamine 2 Receptor Antagonists (H2RA) : cimetidine 1st Generation, ranitidine and famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q 
Treat:
Peptic Ulcer Disease (PUD)
GERD
Stress Ulcer 
Prophylaxis (SUP)
Immune responses (histamine blockade)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Cimetidine
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Histamine 2 Receptor Antagonists (H2RA) : cimetidine 1st Generation, ranitidine and famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

1st Generation

Famotidine
Cimetidine
Ranitidine

A

Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

2nd Generation

Famotidine
Cimetidine
Ranitidine

A

Famotidine

Ranitidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Anti-Androgen

Famotidine
Cimetidine
Ranitidine

A

Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Liver Enzyme Inhibition

Famotidine
Cimetidine
Ranitidine

A

Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Cleaned up version (no androgen/liver issues)

Famotidine
Cimetidine
Ranitidine

A

Ranitidine

Famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Can accumulate in renal impairment (geriatrics)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Cimetidine
Ranitidine
Famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q 
Change pH in the gut- High risk for Pneumonia & C Diff?	
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Cimetidine

Ranitidine/ Famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

KIDNEY DISEASE/GERIATRICS: Can take at night b/c of drownesness. Cns - confusion, hallucinations and disorientation.

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Cimetidine

Ranitidine/ Famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

PH CHANGE IN GI TRACT- Pneumonia & C Diff, notify prescriber of foul smelling/greenish diarrhea.

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Cimetidine

Ranitidine/ Famotidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

ANTI-ANDROGEN: ? may induce impotence and gynecomastia. ? blocks androgen, educate patients to monitor for libido changes, gynecomastia, impotence

Cimetidine
Ranitidine/ Famotidine

A

Cimetidine

42
Q

Renal impairment (begins to act like Benadryl-H1RA)

Cimetidine
Ranitidine/ Famotidine

A

Cimetidine

43
Q

Thrombocytopenia and Hepatotoxicity have been reported- rare

Cimetidine
Ranitidine/ Famotidine

A

ranitidine and famotidine

44
Q

Cimetidine
Ranitidine/ Famotidine
Intended Use
Intended Outcome: Reduced heartburn/dyspepsia/healing of ulcers•NOTE: USUAL DURATION is ?-? weeks for Ulcer healing. •

45
Q

Cimetidine
Ranitidine/ Famotidine
Long term use is indicated for (hypersecretory or hyposecretory) conditions

A

hypersecretory

46
Q

? interacts with many drugs- caution with other drugs

Cimetidine
Ranitidine/ Famotidine

A

Cimetidine

47
Q 
Cimetidine
Ranitidine/ Famotidine 
Administration 
H2RAs and antacids should be administered at least ?-? hours apart
Can administer at bedtime or with meals
A

1-2 hours apart

48
Q

Can administer at bedtime or with meals

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Cimetidine

Ranitidine/ Famotidine

49
Q

Treat:
G.I. Bleed, Peptic Ulcer Disease (PUD), GERD, Stress Ulcer Prophylaxis (SUP)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

50
Q

MECHANISM OF ACTION
Inhibits H+ / K+ ATPase in parietal cells Decreases acid production; irreversible inhibition

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

51
Q

ADVERSE EFFECTS
Change in gut pH
Increased risk for pneumonia and Clostridium difficile

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

52
Q

Rare antifungals/antivirals may not absorb

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

53
Q

Avoid “vir” or “azole”

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

54
Q

Change in absorption of electrolytes

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

55
Q

Long term –hypomagnesemia

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

56
Q

Long term- hypocalcemia◦Fractures and Osteoporosis (due to hypocalcemia)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

57
Q

Drug to Drug
Other drugs may not absorb efficiently

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

58
Q

Omeprazole (Prilosec)

Intened outcome
Intended Outcome: Reduced heart burn/dyspepsia/healing of ulcers•NOTE: USUAL DURATION is ?-? weeks for Ulcer healing.

59
Q

Omeprazole (Prilosec)

Long term use is indicated for (hypersecretory or hyposecretory) conditions

A

hypersecretory

60
Q

Monitor
For long term treatment complications:
Osteoporosis (Vitamin D + Calcium intake)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

61
Q

Pneumonia/C.Diff (patients monitor S/S)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

62
Q

Magnesium (monitor for muscle cramps, more dangerously- seizures)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

63
Q

Taper off if you can, sudden stoppage can cause rebound hypersecretion of stomach acid

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Omeprazole (Prilosec)

64
Q

Omeprazole (Prilosec)

Administration
Patients should take first thing in the morning, ? minutes before their first meal

65
Q

Treat:
Peptic Ulcer Disease

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

66
Q

Composed of aluminum hydroxide and sulfated sucrose. When ingested, creates a protective barrier/gel at active ulcer sites for up to 6 hours

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

67
Q

Anti-Ulcer: Sucralfate
Composed of aluminum hydroxide and sulfated sucrose. When ingested, creates a protective barrier/gel at active ulcer sites for up to ? hours?

68
Q

BAND AID BARRIER

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

69
Q

Drug to drug
May bind other drugs

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

70
Q

Anti-Ulcer: Sucralfate

ADVERSE EFFECTS
Diarrhea or Constipation

A

Constipation

71
Q

Nursing Considerations
Patients may develop constipation- encourage fiber intake

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

72
Q

Remember, it works for several hours at a time.

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Anti-Ulcer: Sucralfate

73
Q

Anti-Ulcer: Sucralfate

Administration
Administer on ? stomach for best mechanism, ideally ? hour before meals and at bedtime (make a protective barrier in stomach BEFORE you eat!)
Separate administration of other drugs (? hours before/after)

74
Q

Treat:
Ulcers Promotes Cervical Ripening (Labor Induction)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

75
Q

Treat Postpartum Hemorrhage

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

76
Q

Can be used for termination of Pregnancy

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

77
Q

MECHANISM OF ACTION
Prostaglandin analog- suppress stomach acid
promote secretion of bicarbonate and mucus

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

78
Q

Promotes Cervical Ripening (cervix becomes thinner- facilitates labor)
Can be used for termination of Pregnancy– stimulates uterine contractions

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

79
Q

ADVERSE EFFECTS
Diarrhea (up to 40%) and abdominal pain (up to 20%)
Spotting, dysmenorrhea

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

80
Q

Pregnancy Category X

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

81
Q

Nursing Considerations
If using the drug, must have negative serum pregnancy test prior to use and be educated about risks.

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

82
Q

Avoid touching this medication with hands (precautions for nurses!)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

83
Q

Educate patients they may have dysmenorrhea, spotting
Educate patients that diarrhea is fairly common

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

84
Q

Administration
Give with meals (reduce GI upset)

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Prostaglandin Analog: Misoprostol

85
Q

Treat:
Gas Pain

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Simethicone

86
Q

MECHANISM OF ACTION
Decreases the surface tension of gas bubbles, gas bubbles become smaller, easier to leave

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Simethicone

87
Q

Commonly given with antacids because they can produce gas

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Simethicone

88
Q

Administration
Comes in chewable tablets/liquids

Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Cimetidine
Ranitidine/ Famotidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Simethicone

89
Q

Treat:
Diarrhea (traveler’s diarrhea)
Indigestion/Heartburn

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

Bismuth Subsalicylate

90
Q

MECHANISM OF ACTION
? component has bactericidal properties
? component may act as anti-inflammatory

Bismuth
Subsalicylate

A

Bismuth

Salicylate

91
Q

ADVERSE EFFECTS
May stain tongue, bowel movements green/black

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

Bismuth Subsalicylate

92
Q

Avoid in children (especially if they have a virus > risk for Reye’s Syndrome)

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

Bismuth Subsalicylate

93
Q

Chronic use could accumulate (risk for salicylism)

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

Bismuth Subsalicylate

94
Q

Drug to Drug
Can bind to antibiotics/other drugs

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

Bismuth Subsalicylate

95
Q

Treat:
Minimum of two antibiotics prescribed (up to three may be used) to reduce risk of resistance developing FOR ?WEEKS (? days)
Amoxicillin, Clarithromycin, Bismuth compounds, Tetracycline, Metronidazole

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

2
14

H. pylori Treatment

96
Q

Nursing Considerations
None is effective aloneIf these drugs are used alone, the risk of resistance developing increases

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

H. pylori Treatment

97
Q

Administration
OAC (Omeprazole, amoxicillin, clarithromycin)

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

H. pylori Treatment

98
Q

BMT (Bismuth Subsalicylate, Metronidazole, Tetracycline)

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

H. pylori Treatment

99
Q

LAC (Lansoprazole, Amoxicillin, Clarithromycin)

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

H. pylori Treatment

100
Q

TIP: These are used to treat H.pylori induced PUD

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

H. pylori Treatment

101
Q

PUD- three letters, needs three drugs!14 days

Simethicone
H. pylori Treatment
Bismuth Subsalicylate

A

H. pylori Treatment

102
Q

Prostaglandin Analog

Cimetidine
Omeprazole (Prilosec)
(aluminum, magnesium salts, calcium salts, sodium bicarbonate)
Ranitidine 
Sucralfate (Carafate)
Simethicone
Bismuth subsalicylate
Misoprostol
A

Misoprostol

Phamacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions