Muscle Disorders of Horses Flashcards

1
Q

Where is CPK/creatine kinase stored?

A

Skeletal and cardia muscle

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2
Q

When will CPK/CK be elevated?

A

Rhabdomyolysis

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3
Q

Brownish urine that does not clear on centrifugation + normal plasma color

A

Myoglobinura

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4
Q

Reddish plasma

A

Hemoglobinuria

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5
Q

If an animal has a painful gait and myoglobinuria, what can you diagnose?

A

Myopathy

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6
Q

In which horse breed is HYPP most common?

A

Quarterhorses

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7
Q

Mutation in skeletal muscle sodium channels in which the fail to inactivate (remain open) and cause hyperexcitability of the muscle

A

HYPP

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8
Q

What is the inheritability of HYPP?

A

Autosomal dominant

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9
Q

What e-lyte disorder results from HYPP?

A

Hyperkalemia

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10
Q

What are clinical signs of HYPP?

A

Muscle fasciculations followed by weakness, stiffness, prolapsed 3rd eyelid

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11
Q

What diet should you feed HYPP?

A

Low potassium (timothy hay) w/frequent small meals and regular exercise

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12
Q

What is myotonia?

A

Mild gait abnormality at start of exercise that then diminishes

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13
Q

Dive bomber electromyography indicates what disease?

A

Myotonia

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14
Q

What is a common name for myositis?

A

Tying up

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15
Q

A racehorse that has been overworked and presents with stiff gain, lethargy, and oliguria likely has what condition?

A

Myositis (tying up)

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16
Q

How does myositis affect the kidneys?

A

Pigment nephropathy

17
Q

How does myositis cause renal failure?

A

Large amt of myoglobin filtered by kidney

18
Q

What type of inheritability does HYPP have?

A

Autosomal dominant

19
Q

Which sire can HYPP be traced back to?

A

Impressive

20
Q

Why does hyperkalemia occur with HYPP?

A

Increased muscle contraction

21
Q

What fluids do you use to treat HYPP?

A

NaCl, 5% dextrose