Multi-system Infections Flashcards
enterotoxin
toxic shock syndrome toxin
exfoliation toxin
(virulence factors of what bacteria)
S. aureus
this toxin causes vomiting (food poisoning); stimulates vagus nerve
Enterotoxin
this toxin causes body rash, fever, lowered bp
toxic shock syndrome toxin
this toxin cleaves desmoglein-1 and causes skin to peel apart
exfoliation toxin
this bacteria can cause:
1. food poisoning
2. toxic shock syndrome
3. abscesses
4. osteomyelitis
5. scalded skin syndrome
6. sepsis
Staph aureus
use what drug for methicillin-sensitive strain of Staph
oxacillin
use what drug for MRSA strains of Staph
vancomycin
bacteria that causes UTIs, neonatal meningitis, and hemolytic uremic syndrome and bloody diarrhea
E. coli
treatment for E.coli UTI’s
Bactrim
treatment for E. coli meningitis
(ampicillin+gentamycin) or ceftriaxone
ETEC causes
watery diarrhea
EHEC causes
bloody diarrhea, HUS
(pedestals and shiga toxin)
UPEC causes
UTI’s
(P-type pili)
neonatal meningitis strain of E. coli caused by what virulence factor
K1 capsule
what serotype of E. coli causes HUS and bloody diarrhea
O157:H7
how do you tell different E.coli from each other
NAAT
1 yr ago (painless ulcer(chancre) on penis)
now (macular rash on palms and soles and trunk)
syphillis
what bacteria leads to syphillis, and what shape is it
Treponema pallidum; spirochetes
how to diagnose pathogens not grown in lab
Serology
PCR
tertiary syphillis symptoms
gummas (granulomatous lesions)
gram + rod that is beta-hemolytic and catalase + that can cause neonatal meningitis
Listeria
pregnant women need to avoid soft cheeses due to
Listeria
to treat listeriosis
Ampicillin + gentamycin (synergy)
standard treatment for meningitis in adults
ceftriaxone
to treat listeriosis for penicillin-allergic patients
Bactrim
Acid Fast stain; resistant to multiple antibiotics
Mycobacterium tuberculosis
to treat Mycobacterium tuberculosis
isoniazid
MoA for isoniazid
targets bacteria cell wall (bactericidal)
to treat TB
cycloserine
rifampicin
isoniazid
