Msyasthenia Gravis Flashcards
1
Q
What class of drugs are used in myasthenia gravis treatment?
A
Acetylcholinesterase inhibitors
2
Q
Give an example of an acetylcholinesterase inhibitor
A
Pyridostigmine
3
Q
How does pyridostigmine work?
A
Iinhibits acetylcholinesterase, which increases the amount of ACh left in the NMJ clefts.
4
Q
What are the ADRs of acetylcholinesterase inhibitors?
A
Muscarinic side effects - salivation, sweating, lacrimation, urinary incontinence, diarrhoea, GI hypermotility, emesis and miosis.
