COPD and Asthma Flashcards
What are some fast acting Beta2 agonists?
Salbutamol and Terbutaline
How do Beta2 agonists cause bronchodilation?
Bind to Gs GPCR, reducing calcium influx.
What are some long acting beta2 agonists?
Formoterol and Salmeterol
Name some Beta2 agonist ADRs
Skeletal muscle tremor, arrhythmia and tachycardia
What are methylxanthines?
Adenosine receptor antagonists
Name some methylxanthines
Theophylline and Aminophylline
Name some methylxanthine ADRs
Psychomotor agitation and tachycardia
Name some inhaled muscarinic receptor antagonists
Ipratropium Bromide and Tiotropium Bromide
What is a common muscarinic receptor antagonist ADR?
Dry cough
How do muscarinic receptor antagonists work?
Antagonise respiratory tract M3 receptors, decreasing bronchoconstriction and mucus secretion.
What is the most commonly used inhaled glucocorticoid in asthma users?
Beclometasone