MSRA: Ovarian Cysts & Cancer Flashcards
What are the risk factors for ovarian cancer?
Increasing age
Family history
Genetics: BRCA1,2 and Lynch syndrome
Nulliparity
What is the inheritance pattern of the BRCA gene mutations?
Autosomal dominant
What are the three components of the risk of malignancy index?
Menopausal status
Ultrasound features
CA-125 measurement
What are the worrying features of an ovarian cyst in a post-menopausal woman?
> 5cm, complex, symptomatic
When should tumour markers be measured in a pre-menopausal woman?
Measure LDH, bHCG and aFP if under 40 with a complex ovarian mass
(Probability of germ cell tumour)
What are the features of Meig’s syndrome?
Δ Benign ovarian tumour (fibroma), ascites and pleural effusion
What is the most common ovarian cyst type?
Follicular cyst
What is the most common type of ovarian cancer?
Serous