MSRA: Ovarian Cysts & Cancer Flashcards

1
Q

What are the risk factors for ovarian cancer?

A

Increasing age
Family history
Genetics: BRCA1,2 and Lynch syndrome
Nulliparity

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2
Q

What is the inheritance pattern of the BRCA gene mutations?

A

Autosomal dominant

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3
Q

What are the three components of the risk of malignancy index?

A

Menopausal status
Ultrasound features
CA-125 measurement

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4
Q

What are the worrying features of an ovarian cyst in a post-menopausal woman?

A

> 5cm, complex, symptomatic

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5
Q

When should tumour markers be measured in a pre-menopausal woman?

A

Measure LDH, bHCG and aFP if under 40 with a complex ovarian mass
(Probability of germ cell tumour)

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6
Q

What are the features of Meig’s syndrome?

A

Δ Benign ovarian tumour (fibroma), ascites and pleural effusion

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7
Q

What is the most common ovarian cyst type?

A

Follicular cyst

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8
Q

What is the most common type of ovarian cancer?

A

Serous

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