MS

Question 1

T or F: MS only affects white matter

Answer 1

false, also affects grey matter

Question 2

what virus is present in almost all MS patients?

Answer 2

EBV

Question 3

MS is predominantly a ___cell mediated disease

Answer 3

T cell mediated

Question 4

most common type of MS

Answer 4

relapsing-remitting MS

Question 5

poor prognostic indicators (5)

Answer 5

1. male
2. older onset age
3. posterior fossa sx at onset
4. Af Am
5. residual disability from 1st attack

Question 6

what CSF findings are consistent with MS but not diagnostic

Answer 6

oligoclonal IgG bands

Question 7

B cell mediated disease; aquaporin 4 Ab, transverse myelitis, bilateral optic nerve involvement, cervical SC

Answer 7

neuromyelitis optica (Devic’s disease)

Question 8

febrile illness; kids; monophasic, affects grey &white matter

Answer 8

acute disseminated encephalomyelitis (ADEM)

Question 9

which drug for MS shows improvement in gait and may reduce motor fatigue

Answer 9

fampridine

Question 10

which vitamin can be utilized to supplement MS tx

Answer 10

vitamin D

Question 11

MS is the leading cause of CNS issues in ______.

Answer 11

young ppl

Question 12

what type of neuro exam does MS give?

Answer 12

UMN, both demyelinating + axonal

Question 13

F or M? Geographic? for MS

Answer 13

FEMALE (board tip: most autoimmunes are female); up latitude!

Question 14

Only genetic factor to be identified in MS

Answer 14

HLA class II on Chromosome 6

Question 15

What really determines your risk factors for MS regardless of where you go?

Answer 15

first 15 yrs of life