brain tumor pathology

Question 1

most common primary brain tumor

Answer 1

glioblastoma multiforme

Question 2

most common locations that metastasize to brain (6)

Answer 2

lung > breast >GU> osteosarcoma> melanoma> GI

Question 3

HA, vomiting, papilledema, ocular palsies, altered LOC, back pain

Answer 3

increased ICP

Question 4

what to administer to lower ICP

Answer 4

mannitol

Question 5

location: adult tumors are ____tentorial vs kid tumors are ___tentorial

Answer 5

supra; infra

Question 6

a tumor of the posterior fossa is likely to be in kid or adult?

Answer 6

kid

Question 7

Malignant, prominent necrosis and haemorrhage, crosses corpus callosum, hyperchromatism, pleomorphism, GFAP+, pseudopalisading

Answer 7

glioblastoma multiforme

Question 8

Tight whorling appearance, psammoma bodies

Answer 8

meningioma

Question 9

arises from arachnoid cells, benign, can present with seizures

Answer 9

meningioma

Question 10

Bubbly cytoplasm in stromal cells, benign

Answer 10

hemangioblastoma

Question 11

hemangioblastoma most often occurs in_____

Answer 11

cerebellum

Question 12

which brain tumor can produce EPO

Answer 12

hemangioblastoma

Question 13

patient presents with retinal angioma, then later a tumor in cerebellum is found

Answer 13

hemangioblastoma secondary to VHL

Question 14

Cerebellopontine angle; S100+, CN VIII

Answer 14

schwannoma

Question 15

small round nuclei with perinuclear halo; fried eggs cells and chicken wire vasculature

Answer 15

oligodendroglioma

Question 16

a thick, elongated, worm-like or “corkscrew” eosinophilic (pink) bundle on H&E staining

Answer 16

rosenthal fiber

Question 17

rosenthal fiber, cystic lesion with a mural nodule, GFAP+, child

Answer 17

pilocytic astrocytoma

Question 18

which tumor can send drop metastases to SC

Answer 18

medulloblastoma

Question 19

hydrocephalus, homer wright rosettes, neuroectoderm origin

Answer 19

medulloblastoma

Question 20

Perivascular pseudorosette

Answer 20

Ependymoma