Movement Disorders Flashcards

1
Q

Hypokinetic Disorders (3)

A

Parkinson’s
Progressive Supranuclear Palsy
Multiple system atrophy

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2
Q

Micropath found in PD

A

lewy bodies

  • fried-egg appearance
  • alpha synuclein
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3
Q

Onset and 4 cardinal features

A
ASYMETRIC ONSET
- rest tremor
rigidity
bradykinesia
postural instability LATER
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4
Q

other characteristic features of parkinsonss

A

masked face
stooped posture
hypokinetic dysarthria (slurred speech)
micrgraphia

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5
Q

micrographia

A

parkinsons

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6
Q

masked face

A

PD

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7
Q

shuffling gait with decreased arm swinging

A

PD

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8
Q

hypokinetic dysarthria

A

PD

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9
Q

micrographia

A

PD

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10
Q

REM sleep behavior disorder

A

PD

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11
Q

Neurofibrillary tangles of phospho-tau proteins

A

Progressive Supranuclear Palsy

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12
Q

initial manifestation: decreased ability for voluntary down-gaze

A

Progressive Supranuclear Palsy

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13
Q

supranuclear gaze palsy

A

Progressive Supranuclear Palsy

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14
Q

Key differences in features of PD and PSP

A

PSP:
tremor negative
balance problems are early findings
symmetric rigidity

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15
Q

3 key features of Multiple system atrophy

A

extrapyramidal dysfunction - parkinsonism
autonomic dysfunction
cerebellar dysfunciton

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16
Q

inspiratory stridor

A

Multiple system atrophy

17
Q

involuntary signing/raynauds

A

Multiple system atrophy

18
Q

differences between Multiple system atrophy and PD

A

postural instability early
no tremor
earlier and more severe ANS findings
NO dimentia

19
Q

3 Hyperkinetic disorders

A

huntingtons
tourettes
primary idiopathic dystonia

20
Q

chromosome of HD gene

A

4

21
Q

sustained repetitive twisting that leads to abnormal postures

A

primary idiopathic dystonia

22
Q

gene of primary idiopathic dystonia and inheritance

A

Torsin A
AD inheritance
Ch. 9
low penetrance

23
Q

dromedary gait

A

primary idiopathic dystonia

24
Q

primary generalized dystonia begins

A

in lower extremity

25
Q

primary focal dystonia begins

A

above waist

26
Q

microscopic halmark of wilsons disease

A

Opalski cell

27
Q

most common neuro feature of wilsons

A

kinetic/intention tremor