Morphine Drug Sheet

Question 1

Morphine

- Presentation

Answer 1

10 mg in 1 ml ampul

Question 2

Morphine

- Indications

Answer 2

• Pain Relief
• Sedation to facilite intubation
• Sedation to maintain intubation

Question 3

Morphine

- Contraindications

Answer 3

• Hypersensitivity
• Late second stage labour
• Renal Impairment or failure

Question 4

Morphine

- Precautions

Answer 4

• Hypotension
• Known addiction to opioids
• Current asthma
• Resp Tract burns
• Resp depression
• Elderly/Frail
• Acute Alcoholism
• Monoamine oxidase inhibitors

Question 5

Morphine

- Metabolism

Answer 5

By liver; excrete by kidneys

Question 6

Morphine

- Pathophysiology

Answer 6

Opioid anlagesec

Actions
CNS: Depression leading to analgesia 
CNS: Resp Depression (apnoea)
CNS: Addiction 
CNS: Stimulation causing changes in mood (euphoria)
CNS: Depression of cough reflex 

CARDIO: Vasodilation
CARDIO: Decreased conductivity through the AV node

Question 7

Morphine

- Route

Answer 7

IV
Subcutaneous
IM

Question 8

Morphine

- Side effects

Answer 8

CNS:
Drowsiness 
Resp depression 
euphoria 
Pin-point pupils 
Addiction 
Nausea and vomiting 

CARDIO
Hypotension
Bradycardia

Question 9

Morphine IM
Onset
Peak
Duration

Answer 9

Onset - 10-30 minutes
Peak- 30-60 minutes
Duration 1-2 hours

Question 10

Morphine IV
Onset
Peak
Duration

Answer 10

Onset 2-5 minutes
Peak 10 minutes
Duration 1-2 hours