Morgan and some mendel Flashcards

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0
Q

Morgan experiments with ..

A

fruit flies, provided convincing evidence that chromosomes are the location of mendel’s heritable factors

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1
Q

The first solid evidence associating a specific gene with a specific chromosome came from:

A

Thomas Hunt Morgan, an embryologist

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2
Q

Characteristics the make fruit flies a convenient organism for genetic studies :

A
  • They breed at a high rate
  • a generation can e bred every two weeks
  • they have only four pairs of chromosomes
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3
Q

Morgan noted wild type, or normal, phenotypes that were common in the fly population..

A

traits alternative to the wild type are called mutant phenotypes

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4
Q

in one experiment, he mated male flies with white eyes (mutant) with female flies with red eyes (wild type) the results were:

A

the F1 generation all had red eyes

the F2 generation showed the 3:1 read :white eye ratio but only males had white eyes

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5
Q

sex plinked genes exhibit unique patterns of inheritance

A
  • in humans and some other animals, there is a chromosomal basis of sex determination
  • in humans and other mammals, there are two varieties of sex chromosomes: a larger X chromosomes and a smaller Y chromosome
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6
Q

only the ends of the Y chromosome have regions that are …

A

homologous with the X chromosome

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7
Q

The SRY gene on the Y chromosome codes for the development of

A

testes

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8
Q

Females are

A

XX

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9
Q

Males are

A

XY

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10
Q

Each ovum contains and X chromosome, while a sperm may contain

A

either and X or a Y

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11
Q

Other animals than humans have different methods of …

A

sex determination

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12
Q

inheritance of sex-linked genes

A

the sex chromosomes have genes for many characters unrelated to sex

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13
Q

a gene located on either sex chromosome is called a

A

sex-linked gene
they follow specific patterns of inheritance
(in humans it usually refers to a gene on the larger x chromosome)

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14
Q

for a recessive sex-linked trait to be expressed

A

a female need two copies of the allele

a male needs only one copy of the allele

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15
Q

Linked genes tend to be inherited together because…

A

they are located near each other on the same chromosome

16
Q

each chromosome has..

A

hundreds or thousand of genes

17
Q

linked genes

A

genes located on the same chromosome that tend to be inherited together

18
Q

Morgan did other experiments with fruit flies to see how linkage affects inheritance of two characters: he crossed flies that differed in traits of body colour and wing size. the results were:

A

colour and wing size are usually inherited together in specific combinations (parental phenotypes) he notes that these genes do not assort independently, and reasoned that they were on the same chromosome (but non parental phenotypes were also produced)

19
Q

genetic recombination

A

the production of offspring with combinations of traits differing from either parent

20
Q

the genetic finding of mendel and morgan relate to the …

A

chromosomal basis of recombination

21
Q

Mendel observed that combinations of traits in some offspring differ from either parent.
Parental types:

A

offspring with a phenotype matching one of the parental phenotypes

22
Q

offspring with nonparental phenotypes (new combination of traits):

A

recombinant types or recombinants

23
Q

a 50% frequency of recombination is observed for :

A

any two genes on different chromosomes

24
Q

genes can be linked, but the linkage was incomplete,

A

as evident from recombinant phenotypes

25
Q

some process must sometimes break the physical connection between genes on the same chromosome

A

crossing over of homologous chromosomes

26
Q

genetic map

A

an ordered list of the genetic loci along a particular chromosome
(the farther apart two genes are, the higher the probability that a crossover will occur between them and therefore the higher the recombination frequency)

27
Q

linkage map

A

genetic map of a chromosome based on recombination frequencies

28
Q

distances between genes can be expressed as :

A

map units; one map unit or centimorgan represent a 1% recombination frequency

29
Q

genes that are far apart on the same chromosome can have a recombination frequency near ..

A

50%

such genes are physically linked, but genetically unlinked, and behave as if found on different chromosomes

30
Q

Abnormal chromosome number:

nondisjunction

A

pairs of homologous chromosomes do not separate normally during meiosis
as a result, one gamete receives two of the same type of chromosome, and another gamete receives no copy

31
Q

Aneuplodiy

A

results from the fertilization of gametes in which nondisjunction occurred (offspring with this condition have an abnormal number of a particular chromosome)

32
Q

polyploidy

A

is a condition in which an organism has more than two complete sets of chromosomes
triploidy (3n) is three sets of chromosomes
common in plants but not animals

33
Q

breakage of a chromosome can lead to four types of changes in chromosome structure:

A

deletion
duplication
inversion
translocation

34
Q

deletion

A

removes a chromosomal segment

35
Q

duplication

A

repeats a segment

36
Q

inversion

A

reverses a segment within a chromosome

37
Q

translocation

A

moves a segment from one chromosome to another