DNA Flashcards

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0
Q

daughter DNA molecules

A

each consisting of one parental strand and one new strand

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1
Q

separation of strand

A

parent strands separated

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2
Q

parent molecules

A

2 parent strands attached

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3
Q

Synthesizing a new DNA strand. Enzymes called DNA polymerases catalyze

A

the elongation of new DNA at a replication fork

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4
Q

the antiparallel structure of the double helix (two strands oriented in opposite directions)…

A

affects replication

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5
Q

DNA polymerases add nucleotides only to free 3’ end of a growing strand;

A

therefore a new DNA strand can elongate only in the 5’ to 3’ direction

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6
Q

along one template strand of DNA, the DNA polymerase synthesizes a ___________ continuously, moving toward the replication fork.

A

leading strand

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7
Q

to elongate the other new strand , called the lagging strand,

A

DNA polymerase must work in the direction away from the replication fork. the lagging s strand is synthesized as a series of segments call Okazaki fragments, which are joined together by DNA ligase

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8
Q

The proteins that participate in DNA replication form a large complex, a

A

DNA replication machine

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9
Q

The DNA replication machine is probably stationary during

A

the replication process

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10
Q

DNA polymerases proofed newly made DNA,

A

Replacing any incorrect nucleotides

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11
Q

in mismatch repair of DNA

A

repair enzymes correct error in base pairing

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12
Q

DNA can be damaged by:

A
chemicals
radioactive emission, 
x-rays
uv light
and certain molecules (ex cigarette smoke)
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13
Q

a chromosome consists of a DNA molecules packed together with

A

proteins

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14
Q

the bacterial chromosome is a

A

double stranded, circular DNA molecule associated with a small amount of protein

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15
Q

Eukaryotic chromosomes

A

have linear DNA molecules associated with a large amount of protein

16
Q

Chromatin

A

a complex of DNA and protein, and is found in the nucleus of eukaryotic cells

17
Q

Histones

A

are proteins that are responsible for the first level of DNA packing in chromatin

18
Q

30 nm fiber

A

interactions b/w nucleosomes cause the thin fibre to coil or fold into this thicker fibre

19
Q

300 nm fiber

A

the 30 nm fiber forms looped domains that attach to proteins

20
Q

Metaphase chromosome

A

the looped domains coil further

the width of a chromatid is 700 nm

21
Q

The information content of DNA is in the form of

A

specific sequences of nucleotides

22
Q

The DNA inherited by an organism leads to

A

specific traits by dictating the synthesis of proteins