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Pharmo Test Two Old Test Review > More "remembered Questions" > Flashcards

More "remembered Questions" Flashcards

1
Q

What converts angiotensinogen into angiotensin I

A

renin

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2
Q 
What binds to AT1 that causes vasoconstriction?
A- Angiotensin I
B- Angiotensin II
C- Angiotensinogen
D- Spironolactone
A

B - Angiotensin II

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3
Q

Which of the following is an adverse reaction of ACE Inhibitors (Captopril)?

A

cough

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4
Q

Which of the following does not have an adverse reaction of hyperkalemia?

A- Minoxadil
B- Epelerenone
C–sartan
D–pril

A

A- minoxadil

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5
Q 
Which of the these can be taken orally?
- Apixaban
- Argatroban
- Heparin
– parin (LMWH)
A

apixaban

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6
Q

Which of these can be taken orally, inhalation, intravenous, and subcutaneously?

Sildenafil
Treprostinil
Bosentan

A

Treprostinil

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7
Q

Which receptor does Endothelin-1 bind to that causes vasocontriction, bronchoconstriction and increased aldosterone secretion?

A

ETa

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8
Q

Pulmonary Arterial Hypertension falls under what category?

A

group 1

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9
Q

Nitric Oxide activated what enzyme to increase vasodilation?

A

Guanylyl cyclase

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10
Q

What drug increases intracellular NO concentration?

A

Nitroprusside

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11
Q

What drug lowers intracellular Ca by blocking L-type calcium channels

A

Felodipine

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12
Q

Which of the following has an adverse reaction of hair growth?

A

Spironolactone

there is another answer: minoxidil

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13
Q

Which of these causes vasodilation by inhibiting PDE5?

A

sildenafil

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14
Q

Which of the following blocks Eta receptor and decreases formation of IP3

A

Bosentan

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15
Q

FenoFIBrate increases lipoprotein lipase levels by what mechanism?

A

PPARa nuclear receptors

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16
Q

Binding of PPARa nuclear receptor causes an increase in what?

A

Lipoprotein lipase

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17
Q

Ezetimibe blocks cholesterol absorption through what mechanism?

A

Blocks NPC1L1 transport protein

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18
Q

What’s the first step of atherosclerosis

A

Endothelial dysfunction

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19
Q

Which of these is “good cholesterol”?

A

HDL

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20
Q

What’s the optimal dose of LDL?

A

< 100

21
Q

What risk assessment would you use to determine the 10 year risk of MI or stroke?

A

ASCVD

22
Q

Which fo the following is not a risk factor of atherosclerosis

A

Exercise

23
Q

What is a negative/neutral effect of HG-CoA reductase inhibitors?

A

Inhibition of germ cell migration during development

24
Q

What type of patient would you not give a Statin to?

A

Pregnant patient

25
Q

Which of the following has the highest effect on LDL?

A

–statin

26
Q

What is the function of PCSK-9 enzyme?

A

Promotes degradation of LDL receptors

27
Q

What is the coagulation parameter used for Warfarin?

A

INR

28
Q

DSHEA stands for:

A

Dietary Supplement Health and Education Act

29
Q

On the label of a dietary supplement “Will help kids feel better about homework”
Permissable???
Non-permissable

A

permissible??

30
Q

A recent study was published that a drug is not effective for how people are using it. The FDA has the authority to full the drug from the shelf.
True??
False

A

true ??

31
Q

A patient wants to take 250mg of ginger before treatment and 250mg after treatment. What should you tell her?

A

That’s fine as long as she takes the dose as she described above

32
Q

A patient likes to take Valium but you know they also took Echinacea, which inhibits the enzyme that normally metabolizes Valium. What should you tell the patient?

A

Be careful driving home bc the effects will be increased

33
Q

St. John’s wort affects the most drugs in what substrate category?

A

3A4

34
Q

Which of the following can be used to treat burning mouth?

A

Alpha-lipoic acid

35
Q 
A patient undergoes radiation therapy. Which of the following can you use to prevent oral mucositis?
A- Tea tree oil
B- Chamomile
C- Co-enzyme Q10
D- Tumeric
E- B and D
A

B and D

36
Q

Which of the following should have a warming to avoid drinking alcohol?

A

Valerian

37
Q

A person didn’t like the taste of CHX but they needed something to treat gingivitis. What would you have them use?

A

0.2% TTO and 3X swish and spit

38
Q

Which of the following is an adverse effect of Kava?

A

Liver failure

39
Q

You colleague does not believe in taking or prescribing dietary substances. What would you tell them to do with their patients who might be taking dietary substances?

A- Ask because it can have drug interactions with medications you prescribe
B- Ask because it could cause increased risks in the procedure
C- Both of the above are true
D- There is no need to ask the patient about these supplements.

A

C- Both of the above are true

A- Ask because it can have drug interactions with medications you prescribe
B- Ask because it could cause increased risks in the procedure

40
Q

The 4 Gs cause increased bleeding risk due to what mechanism?

A

Decrease platelet activation and platelet aggregation

41
Q

What are the 3 components of Virchow’s triad?

A

Hypercoagulability, stasis, vessel wall injury

42
Q

Which of the following is true about the intrinsic pathway?

  • All components present in the blood
  • Monitored by Prothrombin Time (PT)
  • Results in the formation of Factor VIIa
  • Presence of Tissue Factor
A

All compnents present in the bllod

43
Q

Which of these is not a Vitamin K dependent clotting factor?

A

factor IV

44
Q

Which of the following is a COX-1 inhibitor?

A

Aspirin

45
Q

Which of the following increases antithrombin III affinity for BOTH Factor Xa and Thrombin?

A

Heparin

46
Q

Which of these is a direct thrombin inhibitor?

A

Dabigatran

47
Q

Which of the following binds to plasminogen and blocks its activation by TPA?

A

Aminocaproic acid

48
Q

Which of the following P2Y12 inhibitors has the shortest onset?

A

Cangrelor

49
Q

What substrate binds to the P2Y12 receptor?

A

ADP

Pharmo Test Two Old Test Review (8 decks)

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