More "remembered Questions" Flashcards

1
Q

What converts angiotensinogen into angiotensin I

A

renin

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2
Q
What binds to AT1 that causes vasoconstriction?
A- Angiotensin I
B- Angiotensin II
C- Angiotensinogen
D- Spironolactone
A

B - Angiotensin II

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3
Q

Which of the following is an adverse reaction of ACE Inhibitors (Captopril)?

A

cough

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4
Q

Which of the following does not have an adverse reaction of hyperkalemia?

A- Minoxadil
B- Epelerenone
C–sartan
D–pril

A

A- minoxadil

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5
Q
Which of the these can be taken orally?
- Apixaban
- Argatroban
- Heparin
– parin (LMWH)
A

apixaban

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6
Q

Which of these can be taken orally, inhalation, intravenous, and subcutaneously?

Sildenafil
Treprostinil
Bosentan

A

Treprostinil

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7
Q

Which receptor does Endothelin-1 bind to that causes vasocontriction, bronchoconstriction and increased aldosterone secretion?

A

ETa

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8
Q

Pulmonary Arterial Hypertension falls under what category?

A

group 1

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9
Q

Nitric Oxide activated what enzyme to increase vasodilation?

A

Guanylyl cyclase

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10
Q

What drug increases intracellular NO concentration?

A

Nitroprusside

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11
Q

What drug lowers intracellular Ca by blocking L-type calcium channels

A

Felodipine

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12
Q

Which of the following has an adverse reaction of hair growth?

A

Spironolactone

there is another answer: minoxidil

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13
Q

Which of these causes vasodilation by inhibiting PDE5?

A

sildenafil

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14
Q

Which of the following blocks Eta receptor and decreases formation of IP3

A

Bosentan

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15
Q

FenoFIBrate increases lipoprotein lipase levels by what mechanism?

A

PPARa nuclear receptors

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16
Q

Binding of PPARa nuclear receptor causes an increase in what?

A

Lipoprotein lipase

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17
Q

Ezetimibe blocks cholesterol absorption through what mechanism?

A

Blocks NPC1L1 transport protein

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18
Q

What’s the first step of atherosclerosis

A

Endothelial dysfunction

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19
Q

Which of these is “good cholesterol”?

A

HDL

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20
Q

What’s the optimal dose of LDL?

21
Q

What risk assessment would you use to determine the 10 year risk of MI or stroke?

22
Q

Which fo the following is not a risk factor of atherosclerosis

23
Q

What is a negative/neutral effect of HG-CoA reductase inhibitors?

A

Inhibition of germ cell migration during development

24
Q

What type of patient would you not give a Statin to?

A

Pregnant patient

25
Which of the following has the highest effect on LDL?
–statin
26
What is the function of PCSK-9 enzyme?
Promotes degradation of LDL receptors
27
What is the coagulation parameter used for Warfarin?
INR
28
DSHEA stands for:
Dietary Supplement Health and Education Act
29
On the label of a dietary supplement “Will help kids feel better about homework” Permissable??? Non-permissable
permissible??
30
A recent study was published that a drug is not effective for how people are using it. The FDA has the authority to full the drug from the shelf. True?? False
true ??
31
A patient wants to take 250mg of ginger before treatment and 250mg after treatment. What should you tell her?
That’s fine as long as she takes the dose as she described above
32
A patient likes to take Valium but you know they also took Echinacea, which inhibits the enzyme that normally metabolizes Valium. What should you tell the patient?
Be careful driving home bc the effects will be increased
33
St. John’s wort affects the most drugs in what substrate category?
3A4
34
Which of the following can be used to treat burning mouth?
Alpha-lipoic acid
35
``` A patient undergoes radiation therapy. Which of the following can you use to prevent oral mucositis? A- Tea tree oil B- Chamomile C- Co-enzyme Q10 D- Tumeric E- B and D ```
B and D
36
Which of the following should have a warming to avoid drinking alcohol?
Valerian
37
A person didn’t like the taste of CHX but they needed something to treat gingivitis. What would you have them use?
0.2% TTO and 3X swish and spit
38
Which of the following is an adverse effect of Kava?
Liver failure
39
You colleague does not believe in taking or prescribing dietary substances. What would you tell them to do with their patients who might be taking dietary substances? A- Ask because it can have drug interactions with medications you prescribe B- Ask because it could cause increased risks in the procedure C- Both of the above are true D- There is no need to ask the patient about these supplements.
C- Both of the above are true A- Ask because it can have drug interactions with medications you prescribe B- Ask because it could cause increased risks in the procedure
40
The 4 Gs cause increased bleeding risk due to what mechanism?
Decrease platelet activation and platelet aggregation
41
What are the 3 components of Virchow’s triad?
Hypercoagulability, stasis, vessel wall injury
42
Which of the following is true about the intrinsic pathway? - All components present in the blood - Monitored by Prothrombin Time (PT) - Results in the formation of Factor VIIa - Presence of Tissue Factor
All compnents present in the bllod
43
Which of these is not a Vitamin K dependent clotting factor?
factor IV
44
Which of the following is a COX-1 inhibitor?
Aspirin
45
Which of the following increases antithrombin III affinity for BOTH Factor Xa and Thrombin?
Heparin
46
Which of these is a direct thrombin inhibitor?
Dabigatran
47
Which of the following binds to plasminogen and blocks its activation by TPA?
Aminocaproic acid
48
Which of the following P2Y12 inhibitors has the shortest onset?
Cangrelor
49
What substrate binds to the P2Y12 receptor?
ADP