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Pharmo Test Two Old Test Review > 2019 Old Exam > Flashcards

2019 Old Exam Flashcards

1
Q

All preganglionic autonomic releases

A

ACH

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2
Q

Postganglionic parasympathetic releases

A

ACH

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3
Q

Postganglionic sympathetic releases

A

NE

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4
Q

If you have dry mouth, what receptor do you want to target

A

M3

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5
Q

Which of the following drugs has the greatest risk of causing orthostatic hypotension?

A

Terazosin

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6
Q

Which of the following drugs has anticholinergic side effects such as dry mouth

A

Lidocaine

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7
Q

What part of the EKG is ventricular repolarization

A

T wave

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8
Q

Irreversible indirect acting cholinergic

A

Sarin

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9
Q

Regeneration of AchE

A

Pralidoxidine

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10
Q

First line agent for someone that has been exposed to nerve gas

A

Pralidoxidine

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11
Q

What would not be fixed by atropine

A

paralysis

because it only works on muscarinic and not on nictoinic

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12
Q

Quaternary amine

A

Glycopyrrolate

used to dry secretions, quaternary amine

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13
Q

What would a pt not have if having cholinergic toxicity

A

Dry mouth

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14
Q

Depolarizing neuromuscular blocker

A

Succinylcholine

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15
Q

Which relieves angina without changing HR or BP

A

Ranolazine

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16
Q

Which one increases intracellular cGMP

A

Isosorbide mononitrate

used for angina and HF, it is the one that increases intracellular cGMP

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17
Q

What breaks down Ach in the blood

A

AchE

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18
Q

Which alpha agonist ( i think it is supposed to be anatagonist) causes orthostatic __

A

Alpha one; hypotension

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19
Q

Which of the following does beta 1 NOT do

A

Bronchodilation

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20
Q

Which of the following does beta 2 do

A

Bronchodilation

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21
Q

KNOW THE ALPHA ONE EFFECTs

A

Vascoconstriction

mydriasis

urinary sphincter constriction

Increased BP

22
Q

In a pt with anaphylaxis, what do you give them

A

0.3 mg of IM EPI

23
Q

Alpha one agonist that helps with short term hypotension and nasal decongestion

A

phenylephrine

24
Q

Which is a PDE 3 inhibitor

A

Milirinone

25
Q

The L in LOT stands for

A

Lorazepam

26
Q

Short acting beta 2 agonist for asthma

A

albuterol

27
Q

What do you not use in asthmatic patients

a. Aspirin, NSAIDS
b. Opiates
c. Antihistamines
d. All of the above

A

all above

28
Q

Aspirin and coumadin adverse effect

A

bleeding

29
Q

What beta blocker should you give an asthmatic patient

A

metaprolol (beta 1 selective)

30
Q

drug variation can be classified as idosyncratic, pharmacokinetic or

A

pharmacodynamic

31
Q

Different outcomes with same concentration and same outcome with different concentrations for drug variation

A

true

32
Q

Lipid distribution increases as you age because of

A

increased body fat

33
Q

What phase of metabolism is not prone to aging

A

2

34
Q

In pregnancy patients, they have increased CO and __ GFR and __ RBF

A

increased, increased

35
Q

Non-covalent modification is depletion of glutathione. What does this do?

A

disrupts the cell defense

36
Q

Anti-epileptic that causes gingival hyperplasia

A

phenytoin

37
Q

How many mutations do you have to have for malignancy?

A

more than 1

38
Q

Teratogens are detrimental and cause cell division issues during

A

blastocyte formation

39
Q

Phase III is caused by

A

K+ movement

40
Q

Product of CO

A

sv x hr

41
Q

What class does Na+ fall under

A

class I

42
Q

Class IV are selective for myocardium

A

nondihydropyridine

43
Q

What drug causes dry mouth

A

disopyramides

44
Q

What drug inhibits the Na/K ATPase

A

digoxin

45
Q

Which one is not a part of acute coronary syndromes

a. Stable ischemic heart disease
b. STEMI
c. NSTEMI
d. Unstable

A

stable ischemic heart disease

46
Q

More than 100 bpm is classified as

A

tachycardic

47
Q

Allergic reactions are often dose independent and not related to the drug’s MOA

A

true

48
Q

When someone an adverse effect to a drug how do you fix it?

A

dose redcuction

49
Q

A drug that inhibits gastic emptying

A

slows absorption

50
Q

Which of the following are endogenous catecholamines

A

NE, epi, dopamine

51
Q

Epinephrine is produced by the adrenal medulla and is released directly into the bloodstream. This makes epi a

A

hormone

Pharmo Test Two Old Test Review (8 decks)

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