Additonal 2019 Exam 3 questions Flashcards
1
Q
- Which has ADR of GI distress (constipation, abdominal pain, nausea, dyspepsia)
A
a. Colesevalam – (bile acid binding agent, not sure if this was the name used)
2
Q
- Which of the following is a PCSK-9 inhibitor?
A
a. Evolocumab
3
Q
- PCSK-9 normally
A
b. Promotes degradation of LDL receptors
4
Q
- What is a negative effect of lipid parameter of bile acid binding agents
A
a. Increase TG
5
Q
- ADR of STATIN
A
a. Myopathy
6
Q
- Question over which can be used for similar results but with no cough as side effect?
A
a. -sartan
7
Q
- IP3 activation results in what?
A
a. Ca release for SR
8
Q
- Which binds factor Xa and prevents prothrombin converting to thrombin?
A
a. Apixaban
9
Q
- Which can be used to increase salivary secretion in a patient?
A
a. Co-enzyme Q10
10
Q
- Chamomile can be used to treat which radiation/chemo side effect?
A
a. Oral mucositis
11
Q
- Which can be used to tx burning mouth?
A
a. Alpha-lipoic acid
12
Q
- How to measure Argatroban?
A
a. aPTT
13
Q
- Which is the shortest onset?
A
d. Cangrelor
14
Q
- Which mediator binds to PAR-1?
A
a. Thrombin
15
Q
x63. Which of the following does not have cGMP in mechanism?
A
a. Hydralazine
16
Q
- Prostacyclin binds IP3, what is end result?
A
a. Stimulates AC, increase in cAMP
17
Q
- Which is the key mediator in fibronlysis?
A
a. Plasmin
18
Q
- What inhibits the final step in platelet aggregation?
A
a. Eptifibatide (or Abcixamab)
19
Q
- If cholesterol and TGs are absorbed from diet, which pathway is used?
A
a. Exogenous
20
Q
- Which is a direct thrombin inhibitor?
A
a. Argatroban (Dabigatran)
