Monoclonal antibodies Flashcards

1
Q

infliximab moa

A

anti-TNF

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2
Q

infliximab use

A

crohns and UC

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3
Q

rituximab moa

A

anti-CD20

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4
Q

rituximab use

A

used in non-Hodgkin’s lymphoma and rheumatoid arthritis

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5
Q

cetuximab moa

A

epidermal growth factor receptor antagonist

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6
Q

cetuximab use

A

used in metastatic colorectal cancer and head and neck cancer

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7
Q

trastuzumab moa

A

HER2/neu receptor antagonist

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8
Q

trastuzumab us

A

used in metastatic breast cancer

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9
Q

alemtuzumab moa

A

anti-CD52

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10
Q

alemtuzumab use

A

used in chronic lymphocytic leukaemia

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11
Q

abciximab moa

A

glycoprotein IIb/IIIa receptor antagonist

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12
Q

abciximab use

A

prevention of ischaemic events in patients undergoing percutaneous coronary interventions

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13
Q

OKT3 moa

A

anti-CD3

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14
Q

OKT3 use

A

used to prevent organ rejection

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15
Q

Nivolumab moa

A

PD-1

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