Anticoagulants MOA Flashcards

1
Q

Aspirin

A

Non reversible COX1 and COX 2 inhibitor

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2
Q

Warfarin

A

Vitamin K antagonist

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3
Q

Clopidogrel

A

ADP receptor antagonist

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4
Q

Rivaroxaban

A

Direct Xa

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5
Q

Fondaparinoux

A

Activates antithrombin III, which in turn potentiates the inhibition of coagulation factors Xa. It is given subcutaneously.

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6
Q

Dabigatran

A

Dabigatran: direct thrombin inhibitor

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7
Q

Bivalirudin

A

direct thromin IN IN

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8
Q

Rixaroxaban

A

Binds directly to factor Xa

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9
Q

Heparin

A

Inhibit antithrombin III
action Activates antithrombin III. Forms a complex that inhibits thrombin, factors Xa, IXa, Xia and XIIa

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10
Q

LMWH

A

Activates antithrombin III. Forms a complex that inhibits factor Xa

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11
Q

Abciximab

A

Glycoprotein IIb/IIIa receptor antagonist

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