Anticoagulants MOA Flashcards
1
Q
Aspirin
A
Non reversible COX1 and COX 2 inhibitor
2
Q
Warfarin
A
Vitamin K antagonist
3
Q
Clopidogrel
A
ADP receptor antagonist
4
Q
Rivaroxaban
A
Direct Xa
5
Q
Fondaparinoux
A
Activates antithrombin III, which in turn potentiates the inhibition of coagulation factors Xa. It is given subcutaneously.
6
Q
Dabigatran
A
Dabigatran: direct thrombin inhibitor
7
Q
Bivalirudin
A
direct thromin IN IN
8
Q
Rixaroxaban
A
Binds directly to factor Xa
9
Q
Heparin
A
Inhibit antithrombin III
action Activates antithrombin III. Forms a complex that inhibits thrombin, factors Xa, IXa, Xia and XIIa
10
Q
LMWH
A
Activates antithrombin III. Forms a complex that inhibits factor Xa
11
Q
Abciximab
A
Glycoprotein IIb/IIIa receptor antagonist