Glomerular Disease Flashcards
What is Rapidly progressive glomerulonephritis also known as ?
crescentic glomerulonephritis
What are the causes of rapidly progressive glomerulonephritis?
Goodpasture’s, ANCA positive vasculitis
What is IgA nephropathy AKA?
Berger’s disease, mesangioproliferative GN
IGA nephropathy typical hx?
typically young adult with haematuria following an URTI
What is Diffuse proliferative glomerulonephritis aka
Post-streptococcal glomerulonephritis
what does diffuse proliferative glomerulonephritis present as?
presents as nephritic syndrome / acute kidney injury
what is Membranoproliferative glomerulonephritis aka?
mesangiocapillary glomerulonephritis
what are the two types of membranoproliferative glomerulonephritis?
type 1: cryoglobulinaemia, hepatitis C
type 2: partial lipodystrophy
3 conditions that present with nephrotic syndrome?
- minimal change disease
- Membranous glomerulonephritis
- Focal segmental glomerulosclerosis
minimal change disease typical hx
child with nephrotic syndrome
membranous glomerulonephritis presentation
proteinuria / nephrotic syndrome / chronic kidney disease
causes of membranous glomerulonephritis
infections, rheumatoid drugs, malignancy
Causes of focal segmental glomerulosclerosis
may be idiopathic or secondary to HIV, heroin
idiopathic
secondary to other renal pathology e.g. IgA nephropathy, reflux nephropathy
HIV
heroin
Alport’s syndrome
sickle-cell
appearance of focal segmental glomerulosclerosis on biopsy
focal and segmental sclerosis and hyalinosis on light microscopy
effacement of foot processes on electron microscopy
presentation of focal segmental glomerulosclerosis
proteinuria / nephrotic syndrome / chronic kidney disease
