Mollicutes Flashcards

1
Q

Mollicutes: general

A

“soft skin”, smallest self-replicating organism
No cell wall- Trilaminar memb., ubiquitous
pleomorphic, poor stainer

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2
Q

Types of mollicutes

A

Hemotrophic and non-hemotropic

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3
Q

T or F

some Mollicutes have a carbo capsule

A

True

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4
Q

mollicutes genome

A

very small, extremely plastic

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5
Q

Non-hemotrophic mollicutes: general

A

Most host-specific
grown on specialized axenic media- slow, CO2 rich, “Fried egg” colonies
mucosal surfaces, moist cool environments

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6
Q

Non-hemotrophic mollicutes: Transmission

A

Direct contact- aerosol or veneral
mechanical in dairies
Vertical in poultry

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7
Q

Non-hemotrophic mollicutes: pathogenesis

A

survive in non-phagocytic cells
Acute septicemic forms
Chronic inflammatory response=tissue damage

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8
Q

Non-hemotrophic mollicutes: virulence factors

A

Peroxide/superoxide- disrupts cell integrity
Urease
Proinflammatory molecules, IgA proteases

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9
Q

Avian mycoplasmosis: types

A

Reportable
M. gallisepticum
M. synoviae
M. melegridis and M. iowae- Turkeys

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10
Q

M. gallisepticum: Clinical signs

A

Chronic resp. disease in chickens
infectious sinusitis in turkeys
decreased egg prod.
House finch conjunctivitis

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11
Q

M. synoviae: clinical signs

A

synovitis- lamness, joint swelling, reduced growth
sternal bursitis in turkeys
subclinical airsacculitis

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12
Q

M. melegridis and M. iowae: clinical signs

A

aircassulitis, skeletal deformities, stunted growth, decreased eggs hatching

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13
Q

Contagious bovine pleuropneumonia (CBPP) is caused by (include ssp. and variant)

A

Mycoplasma mycoides ssp. mycoides
small colony variant
Most virulent in cattle, Reportable

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14
Q

CBPP: clinical signs

A

Resp. disease, subclinical and persistent
acute and/or fatal presentation
resp. distress, coughing, nasal discharge, lethargy, anorexia

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15
Q

M. bovis, californicum, and canadense can all contribute to ___ (in cattle)

A

Mycoplasma mastitis

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16
Q

Mycoplasma mastitis: clinical signs

A

enlarged supra-mammary lymph nodes, dropped milk prod., thick, purulent milk
all four quarters can be affected

17
Q

M. bovigenitalium and ureaplasma diversum causes

A

Urogenital tract infections

18
Q

Contagious caprine pleuropneumonia is caused by (includes ssp.)

A

M. capricolum ssp. capripneumoniae
similar to bovine condition
Reportable

19
Q

M. agalactiae and M. putrefaciens can cause

A

Contagious agalactia of sheep and goats

reportable, febrile mastitis, arthritis, and conjunctivitis

20
Q

M. mycoides (ssp. and variant) in goats and sheep causes

A

ssp. mycoides (large colony variant)
mastitis, pneumonia, bursitis, arthritis- adults
rapid fatal septicemia- kids

21
Q

M. hyopneumoiae causes

A

porcine enzootic pneumonia

Chronic non-prod. cough, unthrifty, decreased weight gain

22
Q

Cause of Polyseroitis in pigs is

A

M. hyorhinis

23
Q

Mycoplasma in Equine

A

M. felis- self limiting pleuritis
M. equirhinitis/fastidiosum- Resp. disease
M. equigenitalium/subdolum- infertility in mares

24
Q

Mycoplasma in felines

A

M. gatae- arthritis

M. felis- conjunctivitis

25
Q

Mycoplasma in Canines

A

M. canis- urogenital disease: prostatitis, cystitis, etc., infertility
M. cynos/spumans- resp. and arthritic asso.

26
Q

Mycoplasma in Murine

A

M. plumonis- mild resp. disease in mice. genital tract infections in rats

27
Q

Non-hemotrophic mycoplasma: diagnosis

A

Culture is difficult

Serology and molecular tests

28
Q

Non-hemotrophic: treatment

A

attenuated live vaccines

tetracyclines, macrolides (some resistance), high failure rates

29
Q

Hemotrophic Mollicutes: general

A

RBC parasites
causes hemolytic anemia
transmission- blood to blood contact, ectoparasites

30
Q

Hemotrophic Mollicutes: clinical signs

A

Icterus, splenomegaly, bone marrow, hyperplasia

31
Q

Hemotrophic Mollicutes: Diagnosis

A

CS, Blood films, PCR

32
Q

Hemotrophic Mollicutes:

treatment

A

correct anemia

tetracyclines

33
Q

Feline infectious anemia is caused by

A

M. haemofelis

34
Q

FIA: clinical signs

A

fever, anemia, weakness, jaundice

35
Q

FIA: treatment

A

blood, doxycycline, flea control