Chlamydiaceae

Question 1

Chlamydiaceae: general features

Answer 1

Gram negative

obligate intracellular

Question 2

two forms of Chlamydiaceae

Answer 2

infective elementary body

metabolically active reticulate body

Question 3

Zoonotic species

Answer 3

C. abortus, C. felis, C. pneumoniae

Question 4

C. felis can cause ___ in kittens

Answer 4

Conjunctivitis

Question 5

C. abortus can cause abortion in ___% of sheep and ___% in goats

Answer 5

Sheep- 30%

Goats- 60-90%

Question 6

Chlamydiaceae life cycle

Answer 6

Elementary body taken up by host cell - transforms into reticular body - differentiates into EB - EB released

Question 7

Chlamydiaceae transmission in humans

Answer 7

Ingestion, Aerosol, direct (eye), possibly veneral

Question 8

C. abortus: transmission

Answer 8

shed in placenta, uterine discharges

ingestion, aerosol, veneral

Question 9

C. felis: transmission

Answer 9

in ocular and nasal secretions

Question 10

C. abortus: pathogenesis

Answer 10

enzootic abortion, stillbirth, weak lambs with healthy dams

males appear asymptomatic

Question 11

C. felis: pathogenesis

Answer 11

conjunctivitis, blepharospasm, chemosis, congestion, ocular discharge
mild rhinitis, pneumonitis

Question 12

C. pneumonia is horses causes

Answer 12

Nothing (trololol)

is asymptomatic

Question 13

Chlamydiaceae: diagnosis

Answer 13

Antigen detection, culture, serology (paired sera)

Question 14

Chlamydiaceae: treatment

Answer 14

Antibiotics

no resistance seen yet

Question 15

Chlamydiaceae: prevention

Answer 15

disease-free replacement, isolate sick, good hygiene, vaccinate
poor survival against disinfection

Question 16

Chlamydiaceae psittcosis: Transmission to humans

Answer 16

inhalation (dry droppings or dust, mouth to beak, direct contact

Question 17

C. psittcosis: species affected

Answer 17

over 100 avians affected

rarely chickens

Question 18

C. psittcosis: incubation period

Answer 18

3 days to several weeks

intermittent shedding, varies per stress

Question 19

C. psittcosis: clinical signs

Answer 19

Anorexia, weight loss, diarrhea, yellowish droppings, sinusitis, resp. distress, nervous signs

Question 20

C. psittcosis: diagnosis

Answer 20

difficult, single test not helpful

culture- embr. eggs, antibody tests, antigen tests, ELISA, IFA, PCR, RIM

Question 21

C. psittcosis: treatment

Answer 21

difficult, fatalities- rapid deterioration, treat birds for 45 days, may have latent infections

Question 22

C. psittcosis: prevention

Answer 22

education and personal protection

disinfect, management, no vaccine