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Bacti Exam 3 > Campylo, Helico, Lawsonia > Flashcards

Campylo, Helico, Lawsonia Flashcards

1
Q

Campylobacteriaceae: general

A

small, G (-), curved rods that appear as a spirocyte in a chain
NO SPORES
polar flagella at one or both ends

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2
Q

C. jejuni and C. coli are the leading causes of

A

Food-borne bacterial gastroenteritis in humans

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3
Q

Campylobacter: virulence factors

A

Cell wall- LPS. C. jejuni- LOS

Capsule, adhesions, flagella, CDT (cytolethal distending toxin), T2SS, T4SS

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4
Q

C. fetus has ____ for serum resistance

A

long O-antigen chains

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5
Q

Campylobacter: growth characteristics

A

Microaerobic, Temp, oxidase-positive (but do not oxidize sugars)

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6
Q

C. fetus ssp. veneralis: transmission

A

venerally- coitus or AI

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7
Q

C. fetus ssp. fetus and C. jejuni: transmission

A

Ingestion of contaminated food/water or aborted fetus fluids

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8
Q

Campylo: enteric transmission

A 
fecal-oral
contaminated food (poultry)
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9
Q

Bovine gential campylobacteriosis causes

A

Bovine fetal anasarca

Metritis- gray/brown foul smelling exudate

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10
Q

Campylo: repro in sheep and goats

A

one of the most common causes of ovine abortion (Storms)

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11
Q

Pathognomonic lesion of Campylo infected fetus

A

Necrotic donut-shape on fetal liver of sheep

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12
Q

about __ % of chicken ceca contain C. jejuni

A

~50%

all may become contaminated at slaughter

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13
Q

Campylo repro in cattle immunity

A

bacteria maybe cleared by normal flora.
Older bulls may be carriers for life
vaccine

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14
Q

Campylo repro in sheep and goats-immunity

A

immune after abortion or vaccine

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15
Q

Campylo: diagnosis

A

direct exam from samples. Isolation, molecular tests

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16
Q

Campylo: treatment

A

Vaccination
Cattle repro- streptomycin
S/G repro- tetracycle resistance
Enteric- macrolides, no vaccine

17
Q

Arcobacter causes

A

Diarrhea, mastitis, abortion in livestock
Gastroenteritis in humans
Fecal-oral transmission

18
Q

Arcobacter: growth

A

aerotolerant, grow at lower temp. will grow on MacConkey

19
Q

Helicobacter: general

A

spiral, curved, G(-)

20
Q

H. pylori causes ___ in humans

A

persistant gastritis, peptic ulcer disease

21
Q

Helicobacter virulence factors

A

Flagella, Urease (ammonium neutralizes gastric acids), adhesions, LPS
Cytotoxin asso. gene pathogenicity island (Cag PAI)
Vaculating Cytotoxin, Cytolethal distending toxin

22
Q

Helicobacter: growth

A

Microaerophilic, slow growing, fastidious

flat, non-pigmented, non-hemolytic colonies

23
Q

Helicobacter: reservior and transmission

A

Gastric mucus layer of many animals

oral-oral and fecal-oral

24
Q

Helicobacter: clinical signs

A

Chronic inflammation
hyperplasia, reduction of mucus, degeneration of glands, necrosis
hepatic inflammation and necrotizing lesions

25
Q

Helicobacter: diagnosis

A

Stained smears of gastric mucosa, urease test, PCR, western blot, FISH
difficult to culture

26
Q

Helicobacter: treatment

A

most are subclinical infections
resistance develops quickly
Combo therapies

27
Q

Lawsonia intracellularis: general

A

G(-), curved rods, obligate intracellular

28
Q

L. intracellularis causes

A

Porcine proliferative enteropathy

29
Q

PPE: infects

A

pigs, equine

“wet-tail” in hamsters/rodents

30
Q

PPE: transmission

A

fecal-oral

31
Q

PPE: virulence factors

A

LPS, T3SS

32
Q

PPE: pathogenesis

A

Must interact with normal flora for disease

infects distal jejunum and ileum, mild inflammation

33
Q

PPE: clinical signs

A

hyperplasia of intestine

“garden host” gut

34
Q

PPE: diagnosis

A

necropsy, stained smears of GI, immunohistochem., PCR

isolation not possible

35
Q

PPE: treatment

A

tetracyclines, tylosin lincomycin, carbodox,

oral, live att. vaccine

Bacti Exam 3 (7 decks)

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