Molecular Genetics Flashcards

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0
Q

Purines

A

Adenine and guanine, double ringed

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1
Q

Pyrimidines

A

Cytosine and guanine, single ringed

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2
Q

How can you tell a new strand from the old strand immediately after replication

A

Methylation which occurs as DNA ages

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3
Q

A complete genome is present in every one of your _____ cells

A

Autosomal

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4
Q

What unwinds the helix

A

Helicase

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5
Q

What keeps the strands unwound

A

Single strand binding proteins (SSB)

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6
Q

DNA gyrase

A

A topoisomerase which relieves overwound DNA resulting from uncoiling by introducing negative supercoils

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7
Q

DNA polymerase

A

Adds individual nucleotides

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8
Q

mRNA in eukaryotes is ______, it only translates into one product. In bacteria it is ______.

A

Monocistronic, polycistronic

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9
Q

rRNA

A

Plays an important part of ribosomes

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10
Q

Template strand is

A

Antisense

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11
Q

Promoters

A

Specialized regions that signal where to begin transcription

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12
Q

Termination sequence

A

RNA polymerase dissociates

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13
Q

3 ways of processing

A
  1. A 5’ guanosyl cap
  2. A poly-A tail
  3. Introns must be removed
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14
Q

Processing happens where

A

Nucleus

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15
Q

How many codons can you make with three amino acids

A

64

16
Q

What role does peptidyl transferase play in protein synthesis

A

It catalyses the formation of a peptide bond

17
Q

Which stages of protein synthesis require energy?

A

All of them

18
Q

Topoisomerase are enzymes involved in

A

DNA replication

19
Q

In the trp operon

A

Transcription is the norm unless a repressor bind

20
Q

Which codons, when in the A site, start termination

A

UGA UAA UAG

21
Q

Some RNA viruses replicate using what enzyme

A

RNA replicase

22
Q

Integrase

A

Puts DNA copy into the host genome

23
Q

Virion

A

A new viral particle

24
Q

What’s it called when a virus leaves via exocytosis

A

Extrusion

25
Q

What is bacteria in the lytic phase called

A

Virulent

26
Q

Plasmids called ____ are capable of integrating into the genome

A

Episomes

27
Q

How many ori do bacteria have

A

1

28
Q

Transformation

A

Integration of foreign chromosome

29
Q

Conjugation

A

Involves a cytoplasmic bridge from donor male (+) to recipient female (-) made from sex pilli

30
Q

Usually the bridge collapses before the full DNA sequence can be moved in conjugation. Cells that have undergone the change are refered to as

A

Hfr or high frequency of recombination

31
Q

Transduction is

A

The carry over using viruses

32
Q

Promoter

A

Where RNA polymerase binds

33
Q

operator consists of

A

nontranscribable region of DNA that can bind a repressor protein

34
Q

what codes a repressor

A

regulator

35
Q

Inducible systems require the presence of a compound known as an ____

A

Inducer