Molecular Genetics Flashcards

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1
Q

Define DNA

A

Nucleic Acid that houses the genetic material for all living organisms

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2
Q

Define RNA

A

Nucleic Acid that is a copy of DNA to be used as a template to make a protein.

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3
Q

What is the monomer used to build DNA?

A

Nucleotides

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4
Q

What type of nucleotide is NOT found in DNA?

A

“U” (Uracil) is only found in RNA.

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5
Q

What determines genetic info in DNA?

A

The orders/sequences of the base pairs.

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6
Q

How does DNA synthesis compare to DNA replication?

A

They are the same.

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7
Q

What phase of the cell cycle does DNA replication occur?

A

“S” (synthesis” phase

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8
Q

Define mutation

A

Change in the DNA sequence during replication

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9
Q

What is the catalyst for DNA replication?

A

The enzyme DNA polymerase (it breaks the H bonds)

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10
Q

What holds base pairs together in order to form DNA strands?

A

Hydrogen bonds between the base pairs

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11
Q

Where does DNA replication take place in a eukaryotic cell?

A

The Nucleus

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12
Q

How does a gene produce proteins?

A

A segment of DNA is copied into RNA; the RNA is then used to build proteins.

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13
Q

What is the function of mRNA?

A

to carry the code from DNA to the protein building apparatus in the cell.

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14
Q

Why is DNA replication considered to be a “semi-conservative” process?

A

It conserves some the the original DNA in the form of the template strand

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15
Q

What are the three steps to DNA replication?

A
  1. Untwist
  2. Unzip
  3. Form H bonds to new strand of base pairs.
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16
Q

Define transcription

A

RNA polymerase binds to DNA to make a copy of the the DNA sequences, which is mRNA

17
Q

Define translation

A

Process in the ribosome where multiple tRNA bases binds to every three bases in mRNA which result in amino acid sequences

18
Q

What determines an amino acid?

A

The codon or triplet set of base pairs on the mRNA

19
Q

During which step does mutation occur?

A

In replication, If base pairing does not occur correctly in replication, a mutation results.

20
Q

How do BRCA genes influence cancer?

A

BRCA genes repair damaged DNA, and act as cancer suppressors. If these mutate, cancer usually develops.