Classical Genetics Flashcards

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1
Q

Mendel’s Law of Segregation

A

Alleles are segregated or separated into different cells through the process of meiosis.

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2
Q

What type of dominance did Mendel study?

A

Simple dominance, exhibiting a trait from either one parent or the other

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3
Q

Explain incomplete dominance

A

The heterozygous gene(otype) exhibits an intermediate phenotype. Ex. cross between red and white flowers producing pink

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4
Q

Explain codominance

A

Both phenotypes show up, Ex. Cross between red and white flowers producing red/white spotted flowers instead of pink

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5
Q

Explain polygenic inheritance

A

When one phenotype is controlled by multiple genes being present and/or interacting with one another

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6
Q

How do traits “skip” a generation?

A

If a trait is caused by a recessive allele, only homozygous recessive kids will have the phenotype, all heterozygous kids will just be carriers. It may take few generations for a homozygous recessive child to be born.

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7
Q

What kind of trait shows up in every generation?

A

A trait caused by a Dominant allele.

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8
Q

What is a sex-linked disorder?

A

A gene that is present on one of the sex (X or Y) chromosomes.

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9
Q

Why are most sex linked disorders caused by the mother?

A

The male (Y) chromosome is very small, and usually only contains sex determining genes. The female (X) chromosome is much bigger and can hold extra and possible defective genes.

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10
Q

What are some sex linked disorders?

A

Hemophilia, Color-blindness,

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11
Q

How does a dominant disorder pass to future generations?

A

It doesn’t present itself until after the carriers reach reproductive age, this way they make more children before they realize they have it.

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12
Q

How do disorders that affect children get passed down?

A

They are recessive, and pass on through the heterozygous carriers, who are not afflicted but pass on the gene to their children.

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13
Q

What are autosomes?

A

The other 22 pairs of chromosomes that do NOT determine sex.

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14
Q

Why are males more likely to be color blind?

A

Colorblindness is a recessive trait on the x chromosome, the male only gets one of these alleles since he only has one X chromosome. If its recessive he will have color blindness. Whereas a female has the opportunity to get two alleles, if just one of her alleles is Dominant she will not have colorblindness.

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15
Q

What is a karyotype?

A

A picture of chromosomes during mitosis.

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16
Q

What causes Down Syndrome?

A

Trisomy 21 (3 of #21 chromosomes instead of 2)

17
Q

What causes Klinefelter syndrome?

A

Trisomy 23 (2 X and 1 Y chromosome).

18
Q

What causes Turner Syndrome?

A

Only 1 X chromosome

19
Q

What causes Edward’s and Patau’s Syndrome?

A

Trisomy 18 and Trisomy 13

20
Q

Disjunction causes extra or missing chromosomes. Explain disjunction.

A

When cells fail to separate the chromosomes during anaphase in either Meiosis 1 or 2.