Molecular Biology: Lipoprotein Structure and Function

Question 1

What lipoprotein is this?

Answer 1

Question 2

Complete each step

Answer 2

Question 3

• Describe what the generation of, the TAG composition, the cholesterol composition, and function of:
  
  • HDL
  • LDL

Answer 3

Question 4

What is the purpose of the LCAT enzyme?

What additional molecule does it need?

Answer 4

Convert cholesterol bound to HDL into cholesteryl ester using a lecithin molecule

Question 5

HDL Mediates the Formation of LDL

What is happening from 1 to 4 in this figure?

Answer 5

Question 6

Which apolipoprotein is associated with these?

Answer 6

Question 7

Describe each step

Answer 7

Question 8

What lipoprotein is this?

Answer 8

Question 9

If a cell needs cholesterol, what are the two ways that it can get it?

Answer 9

Make it or increase LDL receptors

Question 10

What are the two receptors in the liver that are able to bind chylomicron-remnants?

Answer 10

Question 11

Which apolipoprotein is associated with chylomicrons and chylomicron remnants?

Answer 11

• Top: chylomicron
• Bottom: chylomicron remnants

Question 12

What is CETP?

Answer 12

Question 13

About ___% of Lipids in the blood is cholesterol, with ____ being actual cholesterol and _____ being esterified cholesterol

Answer 13

Question 14

What lipoprotein is this?

Answer 14

Question 15

What enzyme is described?

Answer 15

Question 16

• Describe what the generation of, the TAG composition, the cholesterol composition, and function of:
  
  • VLDL
  • Chylomicrons

Answer 16

Question 17

What lipoprotein is this?

Answer 17

Question 18

HDL Mediates the Formation of LDL

What is happening from 5 to 8 in this figure?

Answer 18

Question 19

About ___% of Lipids in the blood is triglycerides and ____% are phospholipids

Answer 19

Question 20

• What must occur before Triglycerides can enter a cell?
  
  • What is the exception to this?

Answer 20

Question 21

• What are the TRIACYLGLYCEROL carriers?
• What are the CHOLESTEROL carriers?

Answer 21

Question 22

What is the function of Lipoprotein Lipase?

Answer 22

Question 23

About ____ % of fatty acids are bound to albumin

Answer 23

Question 24

What is the purpose of the ACAT enzyme?

Answer 24

Convert intracellular cholesterol to the cholesteryl ester

Question 25

What enzyme is described?

Answer 25

Question 26

What is the function of Hepatic Lipase?

Answer 26

Question 27

What goes on the outer regions of a protein and what goes in the inner regions?

Answer 27

• Outer
  
  • Peripheral proteins
  • Phospholipids
  • Some nonesterified cholesterol may sick through the phospholipids
• Inner
  
  • Integral proteins
  • Cholesteryl-ester
  • Triglycerides