Molecular Basis Flashcards

1
Q

Basic unit of DNA + structure
3 types on bonds
Backbone + ends

A

Nucleotide
1. Phosphate
2. Sugar deoxyribose [ o removed from C2]&raquo_space;»in rna ribose
3. Nitrogenous bases
Purine ( adenine + guanine )
Pyrimidine (cytosine + thymine)
Thymine aka 5 methyl uracil
In rna uracil

NGlycosidic linkage
Nitrogenous base - OH of c1

Phosphoester linkage
P grp- OH of c5

Phosphodiester linkage
Nucleotide- Nucleotide

Backbone =
Phosphodiesterbond+Sugar + Pi

5* free phosphate grp
3* free OH

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2
Q

Erwin chargaff

A

Not applicable to ss RNA
> A+G = C+T [purine =pyrimidine]
>amount of sugar =amount of pi
>no.of pi = no.of nitrogenous bases
>A+T/C+G = const 1.52H 0.93E

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3
Q

Salient features of dna

A

> 2 chains Backbone + nitrogenous bases projected inwards
anti polarity 5>3 3>5

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