Module 9 Flashcards
What is immunology?
How does your body react to microbes?
Compare innate vs adaptive immunology
What are the physical defences of innate immunity
What are chemical defences of innate immunity
Describe the complement system of innate immunity
Enzymes create MAC by ‘drilling’ a hole in the membrane skewing the osmotic gradient and killling bacteria
Can be activated by antibody-antigen complex classical pathway (adaptive) or mannose-binding lectin pathway (innate)
-opsonization is the coating of the target that makes the immune system easier to react
What are cytokines and chemokines and their functions
What are interferons and their function
What organs are involved in immunity
What are the cell types involved in innate immunity
Derived from pluripotent hemtopoietic stem cells (HSCs)
-Erythrocytes (red blood cells)
-Leukocytes (white blood cells)
-Platelets
Granulocytes
-Can be stained
-Toxins and enzymes
-Destroys their targets
What are the roles of the cell types in innate immunity
Describe phagocytosis in innate immunity
How are pathogens recognized in innate immunity
How are microbes killed without phagocytosis
Describe inflammation
Describe fever
What is adaptive immunity
What are antigens and immunogens?
What are epitopes?
What are antibodies?
What are the immunoglobulin classes
Explain the major histocompatibility complex (MHC)
Explain antigen presentation
Describe cell-mediated aquired immunity
Explain T cell selection
What are the T cell classes
What are T cell receptors
What are helper T cells and their subtypes
What are cytotoxic T cells
Explain B cell selection and the production of antibodies
Explain T-cell independent production of antibodies
Explain T-cell dependent production of antibodies
What are the different types of vaccines and their effects
