Module 9 Flashcards

1
Q

What is immunology?

A
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2
Q

How does your body react to microbes?

A
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3
Q

Compare innate vs adaptive immunology

A
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4
Q

What are the physical defences of innate immunity

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5
Q

What are chemical defences of innate immunity

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6
Q

Describe the complement system of innate immunity

A

Enzymes create MAC by ‘drilling’ a hole in the membrane skewing the osmotic gradient and killling bacteria
Can be activated by antibody-antigen complex classical pathway (adaptive) or mannose-binding lectin pathway (innate)
-opsonization is the coating of the target that makes the immune system easier to react

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7
Q

What are cytokines and chemokines and their functions

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8
Q

What are interferons and their function

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9
Q

What organs are involved in immunity

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10
Q

What are the cell types involved in innate immunity

A

Derived from pluripotent hemtopoietic stem cells (HSCs)
-Erythrocytes (red blood cells)
-Leukocytes (white blood cells)
-Platelets

Granulocytes
-Can be stained
-Toxins and enzymes
-Destroys their targets

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11
Q

What are the roles of the cell types in innate immunity

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12
Q

Describe phagocytosis in innate immunity

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13
Q

How are pathogens recognized in innate immunity

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14
Q

How are microbes killed without phagocytosis

A
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15
Q

Describe inflammation

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16
Q

Describe fever

17
Q

What is adaptive immunity

18
Q

What are antigens and immunogens?

19
Q

What are epitopes?

20
Q

What are antibodies?

21
Q

What are the immunoglobulin classes

22
Q

Explain the major histocompatibility complex (MHC)

23
Q

Explain antigen presentation

24
Q

Describe cell-mediated aquired immunity

25
Explain T cell selection
26
What are the T cell classes
27
What are T cell receptors
28
What are helper T cells and their subtypes
29
What are cytotoxic T cells
30
Explain B cell selection and the production of antibodies
31
Explain T-cell independent production of antibodies
32
Explain T-cell dependent production of antibodies
33
What are the different types of vaccines and their effects