Module 10 Flashcards

1
Q

What is epidemiology and public health

A
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2
Q

What is mortality, morbidity and DALY

A
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3
Q

What is incidence and prevalence

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4
Q

What are the different patterns of incidence

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5
Q

What is herd immunity

A
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6
Q

What is basic reproduction number (Ro)

A

above 1 becomes alarming

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7
Q

What is the scope and stages of disease

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8
Q

What are the types of epidemics

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9
Q

What are the modes of disease transmission

A
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10
Q

What are carriers

A
  • Pathogen-infected individuals showing no signs of clinical disease
  • Potential sources of infections
  • May be individuals in the incubation period of the disease
  • Can be identified using diagnostic techniques, including culture and
    immunoassays
  • Typhoid Mary is an example of a carrier
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11
Q

Describe the host community

A
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12
Q

What are reservoirs and zoonosis

A
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13
Q

What are the lab classifications according to their biosafetly level (BSL)

A
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14
Q

Describe the workflow for clinical identification of microorganisms

A
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15
Q

Describe how pathogens can be collected from different sites

A
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16
Q

What are the 4 ways to identify microorganisms

A

-Microscopy
-Culture
-Biochemical tests
-Molecular tests

17
Q

Describe how to identify microorganisms by culturing

18
Q

Describe how biochemical tests are used to identify microorganisms

19
Q

Describe how molecular tests (PCR) are used to identify microorganisms

20
Q

How can Neisseria gonnorhoeae can be identified

21
Q

How are immunoassays used for infectious diseases

22
Q

What is a precipitation reaction

23
Q

What are direct agglutionation tests

24
Q

What are passive (indirect) agglutination tests

25
What are neutralization tests
26
What is immunofluorescence
27
What are direct and indirect enzyme immunoassays (EIAs)
28
What are rapid immunological tests
29
What are western blots
30
What is genomics
31
What are the three generations of DNA sequencing technology
32
Describe the sanger DNA sequencing method
33
Describe the nanopore minion
34
What is annotation and bioinformatics
35
What is transcriptomics and microarrays
Information derived from microarrays: -Global gene expression * Expression of specific groups of genes under different conditions * Expression of genes with unknown function; can yield clues to possible roles * Comparison of gene content in closely related organisms * Identification of specific organisms
36
Describe RNA-sequencing in transcriptomics
37
Describe proteomics
38
Describe metabolomics