Module 4 poll and assignment

Question 1

What is the central dogma?

a. DNA to protein to RNA
b. DNA to RNA to protein
c. RNA to DNA to protein
d. Protein to RNA to DNA

Answer 1

b.

Question 2

What is the consequence of having bidirectional replication?

a. the creation of leading and lagging strand
b. the creation of an Okazaki fragment
c. the creation of a discontinuous fragment
d. The need for two DNA polymerases to be attached to the replisome
e. all of the above

Answer 2

e.

Question 3

Which component(s) is/are essential for DNA replication?

a. primase
b. DNA ligase
c. DNA ligase
d. RNA polymerase
e. Helicase
f. None of the above

Answer 3

a,b,d

Question 4

Why do bacteria have more than 1 sigma factor?

a. it provides genetic regultaion of transcription and helps bacteria respond to their environment

b. it provides redundancy and protects bacteria against the effect of antibiotics

c. Each promotr region in the genome needs their specialized sigma factor to ensure gene expression

d. It is an accidental gene duplication event and provides no additional function

Answer 4

a.

Question 5

Which of the following components is involved in the initiation of transcription?

a. primer
b. origin
c. promoter
d. start codon

Answer 5

c.

Question 6

Which of the following types of RNA codes for a protein?

a. tRNA
b. mRNA
c. rRNA
d. RNase

Answer 6

b.

Question 7

When thinking about the gene (i,e, DNA sequence) the sequence of the tRNA anticodon is

a. the reverse complement of the DNA template

b. the complement of the DNA template

c. The exact same sequence of the DNA template (but with Uracil)

d. The reverse of the DNA template

Answer 7

c.

Question 8

which of the following components is involved in the initiation of translation?

a. ribosome binding site

b. start codon

c. promoter

d. primer

Answer 8

b.

Question 9

You are developing a drug that will target a newly identified archaeal pathogen. Your drug targets transcription but exhibits high toxicity towards eukaryotic cells. What is the best explanation?

a. the drug targets the RNA polymerase and prevents its activity

b. the drug prevents the generation of polycistronic mRNA

c. The drug prevents the formation of a stem loop as a termination signal

d. the drug prevents the activity of the Rho protein

Answer 9

a