MODULE 8: THE BIOCHEMICAL ASPECTS OF CANCER (CRUZ)

Question 0

Leukemias and lymphomas arise from what type of cells?

Answer 0

White blood cells

Question 1

Most common classification of cancer that arises from epithelial cells.

Answer 1

Carcinomas

Question 2

Once cell passes through this stage of the cell cycle it is committed to divide.

A. S phase
B. G1 phase
C. G2 phase
D. M phase

Answer 2

B. G1 phase

Question 3

‘Statins’ drug are known to lower blood cholesterol by inhibiting its synthesis via what enzyme?

Answer 3

HMG-CoA reductase

Question 4

In tumor cells, enhanced activity of __________ contributes to their evasion of normal apoptotic mechanisms.

Answer 4

Telomerase

Question 5

Plays a role in the regulation of the transcription factor activity.

Answer 5

Retinoblastoma factor

Question 6

Transcription factor codes for the following genes EXCEPT:

A. DNA polymerase gene
B. THFR gene
C. Cyclin gene
D. Rb gene

Answer 6

D. Rb gene

Question 7

Arrest phase of the cell cycle. The cell has the option to go back or resume in the process of the cycle.

Answer 7

G0 phase

Question 8

A protein that arrests the cell cycle.

Answer 8

Cell cycle division kinase

Question 9

Transcription of this gene leads to the expression of a protein that arrests the cell cycle.

Answer 9

p21