MODULE 3

Question 0

RLE of PPP.

Answer 0

Glucose-6-P dehydrogenase

Question 1

Rate limiting step of PPP.

Answer 1

Glucose-6-P ➡️ 6-phosphogluconate

Question 2

Only __________ can remove H2O2.

Answer 2

Reduced glutathione

Question 3

Deficiency in NADPH oxidase.

Answer 3

Chronic Granulomatous Disease

Question 4

Uronic acid pathway occurs in what organ and cellular site?

Answer 4

Liver, cytoplasm

Question 5

Humans cannot synthesize ascorbic acid because we lack this enyme.

Answer 5

L-gulonolactone oxidase

Question 6

Deficiency of reductase enzyme needed to convert L-xylulose to xylitol.

Answer 6

Essential Pentosuria

Question 7

Converts glucose to sorbitol.

Answer 7

Aldose reductase

Question 8

Converts sorbitol to fructose.

Answer 8

Sorbitol dehydrogenase

Question 9

Fructosuria of this enzyme deficiency is benign.

Answer 9

Fructokinase

Question 10

Galactose-1-P + UDP-glucose ➡️ UDP-galactose + glucose-1-P

This reaction is catalyzed by what enzyme?

Answer 10

Galactose-1-P uridyl transferase

Question 11

Cataracts in early childhood.

Answer 11

Galactokinase deficiency

Question 12

Cataracts within a few days of birth.

Answer 12

Gal-1-P Uridyltransferase deficiency