Module 6 Nervous System Flashcards
Weak compared to morphine, opioid agonist, usually combined
Oxycodone
Oxycodone + ASA
Percodan
Oxycodone + Acetaminophen
Percocet
Oxycodone + Motrin
Combunox
Oxycodone is available as a __________ and is given q ___
Sustained release q 12 hrs
Hydrocodone + Tylenol
Vicodin
Hydrocodone + Ibuprofen
Vicoprofen
Hydrocodone + Codeine
Antitussive
Where does morphine sulfate come from
White poppy plant
What is the drug of choice for post MI, PE
Morphine Sulfate
Short acting Morphine Sulfate lasts for how long
4-5 hrs
How long does the sustained release form of Morphine Sulfate last
(Roxanol) 8hrs
MS contin 12 hrs
4 Side effects of Morphine Sulfate
decreased CNS
Euphoria
Paradoxical excitement
Pinpoint pupils
What is another word for pinpoint pupils
Myosis
What are 3 cases where Morphine Sulfate is contraindicated
COPD
Head injury
Tolerance
Mu, Kappa, and Delta are examples of
Narcotic Analgesics
Works by binding to opiate sites
Narcotic Analgesics
Agonists __________ while Antagonists _________
elicit a response
Do not
An example of an Opioid Agonist is
Morphine
An example of an Opioid Agonist/Antagonist is
Talwin
And example of an Opioid Antagonist is
Narcan
Mimics the neurotransmitter endorphin and Enkephalin that are the bodies natural analgesic to increase pain threshold
Narcotic Analgesics
Drug group that works by changing perception of pain
Narcotic Analgesics
What does morphine attach itself to in the body
the mu receptor site
Narcotic Analgesic Withdrawal can lead to (3)
Diarrhea, large pupils, stomach cramps
Talwin attached itself to
Kappa and Delta sites
When are Agonists-Antagonists used
when patient cant tolerate Agonist
What are 3 side effects of Agonists-Antagonists
Vertigo, euphoria, hallucination
What are 2 advantages of Agonists-Antagonists
less resp depression and less dependency
Pentazocine + ASA
Talwin
Prevents or reverses opiate effects
Antagonist
Salicylates, NSAIDS, and Tylenol are examples of
Analgesic Non-narcotic
What are Analgesic Non-narcotic used for usually
migraine
blocks impulse within the sympathetic nervous system - produces vasoconstriction
Ergot Derivatives
Used to reduce frequency and intensity of migraines
Ergot Derivatives
Bind with vascular receptors to produce vasoconstriction
Triptans
What is a major side effect of Triptans
Fibrosis in heart and lungs (stroke)
How frequent do we administer Triptans
Give for 1 mo, then rest for 4-6 mo
Ergot + Caffeine
Cafergot
Hold drugs when resp is below
12
Pin point pupils are a sign of
toxicity
Allays fear and excitement
Sedatives
Induces sleep
Hypnotics
When are Sedatives / Hypnotics used
Insomnia
What are two types of Sedatives / Hypnotics
Barbiturates and Non Barbiturates
Inhibit the uptake of Gamma aminobutyric Acid
Barbiturates and Non Barbiturates
How are Barbiturates classified
based on onset of action and duration
GABA is a
CNS neurotransmitter
What is the antidote for Barbiturates
Flumazenil (Romazicon)
Up to how long should Barbiturates be used
2 weeks
Barbiturates should not be used to mask pain as it has no
has no analgesic effect
What are the 4 stages in order of Anesthesia
Analgesia
Excitement/Delirium
Surgical Anesthesia
Medullary paralysis
Gases for Anesthesia are usually combined with
Oxygen
What are two drugs that help to balance Anesthesia
Cyclopropane
Nitrous Oxide
General Anesthesia by injection is preferred _____ to gases
prior
Neuroleptanalgesia (Innovar) is used for
moderate to deep sedation
What is a major side effect of Anesthesia
Malignant hyperthermia
Temp 105+ , tachycardia, cardiac arrest are signs of
Malignant hyperthermia
What is the tx for Malignant hyperthermia
Dantrolene (Dantrium)
Used to change permeability of nerve cell, alter nerve conduction
Local Anesthetics
Local anesthetics come from
coca plants
Spinal Anesthesia is given where
into the subarachnoid space between 2nd and 4th
Epidural Anesthesia is given where
epidural space L1 - L2
What are 4 things we must do before inducing Anesthesia
Empty bladder
Ensure post voiding
Baseline B/P, RR
Ensure return of sensation
Pre anesthetic drugs are used to
Decrease anxiety, secretions, and chance of N&V
Abnormal disturbance in electrical activity of the brain means pt. may be experiencing a
seizure
Used to stabilize nerve cell against hyperexcitability
Hydantoins