Module 6 Flashcards

1
Q

Identify the functions of the skeletal system

A

Support
Protection
Movement
Mineral storage
Blood cell production
Storage of energy

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2
Q

What substances make up the intercellular materials of bone?

A

mineral salts (calcium phosphate and calcium carbonate), mainly collagen fibres, and water.

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3
Q

Haversian canal

A

a tiny channel running through compact bone that carries small blood vessels and nerves

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4
Q

canaliculi

A

minute channels radiating out from the lacunae that contain cytoplasmic projections from the osteocytes.

Canaliculi connect osteocytes in the lacunae with each other and with the central canals.

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5
Q

two types of ossification

A

intramembranous ossification-flat bones of skull

endochondrl ossification- all bones during growth

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6
Q

secondary ossification centres

A

develop in the epiphyses and lay down spongy bone, infiltrated by blood vessels.

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7
Q

Epiphyseal plate (line)

A

the structure primarily involved in the increase in the length of long bones

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8
Q

bone remodeling

A

the constant replacement of old bone with new bone.

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9
Q

function of the osteoclasts

A

remove bone during remodelling. They secrete digestive enzymes and acids to attack the bone.

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10
Q

factors required for bone remodelling

A

Ca, P, Mg
vitamins D, A, C, B12
growth hormone
sex hormones

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11
Q

Which two hormones regulate Ca homeostasis

A

Parathyroid hormone (PTH) from the parathyroid glands

calcitonin from the thyroid gland

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12
Q

Concentric lamellae

A

Rings composed of hard, calcified matrix surrounding the Haversian canals

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13
Q

When an osteoblast becomes isolated in a lacuna, it is transformed into a(n)

A

Osteocyte

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14
Q

hemopoesis

A

blood cell formation
occurs in red marrow

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15
Q

where is triglyceride stored

A

yellow marrow

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16
Q

long bones

A

a shaft with two ends
cylindrical
longer than it is wide
function as levers
femur and humerus

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17
Q

short bones

A

cube like
equal in length, width, and thickness
provide stability, support, and some limited motion
carpals and tarsals

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18
Q

flat bones

A

thin and usually curved
points of attachment for muscles
protect internal organs
skull and ribs

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19
Q

irregular bones

A

not long, flat, or short
facial bones
vertebrae

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20
Q

sesamoid bones

A

small and round
shaped like a sesame seed
form in tendons where a great deal of pressure is generated in a joint
protect tendons by helping them overcome compressive forces
patella

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21
Q

what is a long bone composed of (9)

A

diaphysis
epiphysis
metaphysis
hyaline cartilae
periosteum
marrow cavity/medullary cavity
red marrow
yellow marrow
endosteum

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22
Q

diaphysis

A

tubular shaft that runs between the proximal and distal ends of the bone.
the walls are composed of compact bone

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23
Q

epiphysis

A

wider section at each end of the bone
filled with spongy bone
red marrow fills the spaces of spongy bone

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24
Q

metaphyses

A

area between diaphysis and epiphysis
includes epiphyseal plate

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25
hyaline cartilage/articular cartilage
at ends of bones reduces friction and absorbs shock at freely moveable joints
26
periosteum
CT that covers the surface of bones contains osteogenic cells protects bone assists in fracture repair helps nourish bone tissue serves as an attachment site for ligaments and tendons contains blood vessels, nerves, and lymphatic vessels
27
what makes up the microscopic structure of bone (4)
osteoprogenitor cells osteoblasts osteocytes osteoclasts
28
osteoprogenitor cells
precursor cells
29
osteoblasts
bone building cells
30
osteocytes
mature bone cells principle cells of bone tissue
31
osteoclasts
derived from monocytes and serve to break down bone tissue
32
what does bone matrix contain
inorganic salts (hydroxyapatite) calcium carbonate collagen fibres
33
what makes bones hard
mineral salts
34
what gives bones tensile strength
collagen fibers
35
intramembranous ossification
the formation of bone directly from with the fibrous CT membranes
36
endochondral ossification
bone formation from hyaline cartilage models involves the replacement of cartilage
37
what are the 4 steps of intramembranous ossification
1. osteoblasts cluster at the centre and begin to specialize. 2. osteoblasts secrete uncalcified matrix, which hardens within a few days. 3. osteoblasts turn into osteocytes and lay down trabeculae to form spongy bone. 4. the outer surface is covered with periosteum.
38
what are the 8 steps of endochondral ossification?
1. mesenchymal cells become chondrocytes. 2. perichondrium appears. 3. more matrix, chondrocytes grow 4.matrix calcifies and kills chondrocytes 5.blood vessels replace the chondrocytes and bring osteogenic cells 6.cartilage grows, capillaries penetrate 7. perichondrium turns into periosteum 8. osteoblasts form periosteal collar of compact bone
39
calcium and vitamin d
bone remodelling
40
vitamin k
bone minerallization regulates bone growth
41
magnesium
bone structure
42
fluoride
strengthens and stabilizes bone minerals bone density
43
omega-3
enhance production of new osseous tissue
44
axial bones
forms the vertical, central axis includes all bones of the head, neck, chest, and back 80 bones protects brain, spinal cord, heart, and lungs
45
appendicular bones
all bones of the upper and lower limbs plus the bones that attach each limb to the axial skeleton 126 bones
46
articulations
where two bones meet
47
head
prominent rounded surface
48
facet
flat surface
49
condyle
rounded surface
50
projections
raised markings
51
protuberance
protruding
52
process
prominence feature
53
spine
sharp process
54
tubercle
small rounded process
55
tuberosity
rough surface
56
line
slight, elongated ridge
57
crest
ridge
58
holes
holes and depressions
59
fossa
elongated basin
60
fovea
small pit
61
sulcus
groove
62
canal
passage in bone
63
fissure
slit through bone
64
foramen
hole through bone
65
meatus
opening into canal
66
sinus
air-filled space in bone
67
growth hormone
triggers chondrocyte proliferation in epiphyseal plates resulting in the increasing length of the long bones increases calcium retention
68
thyroxin
promotes osteoblastic activity and the synthesis of bone matrix
69
estrogen and testosterone
promote osteoblastic activity and production of bone matrix promote the conversion of the epiphyseal plate to the epiphyseal line
70
calcitrol
active form of vitamin d produced by kidneys stimulates the absorption of calcium and phosphate from the digestive tract