Module 22 Obesity Flashcards
IBW calculation
Male height cm - 100
Female height cm - 105
BMI formula
Body weight kg / height m2
Waist circumference greater than what denotes increased risk of metabolic syndrome
Men 40 inches
Women 35 inches
Respiratory changes in obesity
Reduced lung volumes- restrictive pattern of breathing
Decreased ERV
High risk of OSA if STOP BANG score is
> 3
Define obesity hypoventilation syndrome
BMI > 30
Daytime hypoventilation
Awake PC02 > 45mmHg
Systemic HTN causes what type of hypertrophy in obesity
Eccentric hypertrophy
Concentric in normal weight people
Which drugs are dosed off LBW
Water soluble
Which drugs dosed off total body weight
Lipid soluble
Single major predictor of problematic intubation in morbidly obese
Neck circumference
Forearm BP measurement
Overestimates SBP and DBP
Extubation criteria in obese
TV
VC
TV > 5ml/kg IBW
VC >10-15ml/kg
Where is ADH synthesized?
Stored
Synthesized in supraoptic and paraventricular nuclei of hypothalamus
Stored in posterior pituitary
Differentiate central diabetes insipidus and nephrogenic diabetes inspidus
Central is due to failure to release ADH
Nephrogenic is renal tubules fail to respond to ADH
What is the treatment for DI
DDAVP
Parathyroid gland regulates what
Calcium and phosphate
Disease with triad of hyperthyroidism, exopthalamus, and dermopathy
Grave’s disease
Abnormally low levels of thyroxine result in what condition in children
Adults
Cretinism in children
Myxedema in adult
What hormone inhibits gastrointestinal motility and secretion
Somatostatin
Biochemical triad in DKA
Ketonemia
Hyperglycemia
Acidemia
Where is aldosterone secreted
Zona glomerulosa of adrenal cortex
Action of aldosterone
Sodium retention
Potassium excretion
Excessive cortisol levels is what disorder
Cushing’s syndrome
Cushing’s is due to
Overproduction of ACTH by anterior pituitary
What disease is caused by destruction of the adrenal glands
Addision’s disease
Primary adrenal insufficiency
Hypersecretion of aldosterone is what disorder
Conn’s Syndrome
Primary hyperaldosteronism
What electrolyte abnormalities are seen in Addison’s
Hyperkalemia
Hyponatremia
Due to deficiency in aldosterone